ID   K2NN64_TRYCR            Unreviewed;       339 AA.
AC   K2NN64;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF30302.1};
DE   Flags: Fragment;
GN   ORFNames=MOQ_005890 {ECO:0000313|EMBL:EKF30302.1};
OS   Trypanosoma cruzi marinkellei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF30302.1, ECO:0000313|Proteomes:UP000007350};
RN   [1] {ECO:0000313|EMBL:EKF30302.1, ECO:0000313|Proteomes:UP000007350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|EMBL:EKF30302.1,
RC   ECO:0000313|Proteomes:UP000007350};
RX   PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA   Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA   Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA   Andersson B.;
RT   "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT   with the bat-restricted subspecies T. cruzi marinkellei.";
RL   BMC Genomics 13:531-531(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKF30302.1}.
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DR   EMBL; AHKC01012254; EKF30302.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2NN64; -.
DR   EnsemblProtists; EKF30302; EKF30302; MOQ_005890.
DR   OrthoDB; 3887240at2759; -.
DR   Proteomes; UP000007350; Unassembled WGS sequence.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR008377; Sialidase_trypan.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13859; BNR_3; 1.
DR   PRINTS; PR01803; TCSIALIDASE.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          51..338
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EKF30302.1"
FT   NON_TER         339
FT                   /evidence="ECO:0000313|EMBL:EKF30302.1"
SQ   SEQUENCE   339 AA;  36990 MW;  931D8B513F730604 CRC64;
     FRGAAPRRDD VLRHCGAAQD AEPAPAKELS SRSPFDWRDT TGDEKVSSLH VPSLVEVDGG
     VFAVAEAQCT KEDESGFTGI ASELLTWTNE KPEDLDMSKL KVQLLDECTP GEGLCRSKTA
     VPVVSLTLKD VNVSRPTAVV NGSDIYMLAG NYSIGGAATS DAVQWGLLLV KGNISDTEEK
     DKRIYWNDTY GLPWDIFEEH ESLTRLIGSG GSGVKMQDGT FLFPVEGTKK ENNKTVSLIL
     YWNGNKSWTL SKGMSADGCS DPSVVEREKD KLMMMTACDD GRRRVYESGD KGESWTEALG
     TLSRVWSNNQ KGGSGFITAK IEERGVMLVT LPVYPKEKG
//