ID K2NW65_TRYCR Unreviewed; 1068 AA.
AC K2NW65;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 03-MAY-2023, entry version 39.
DE SubName: Full=ATPase, putative {ECO:0000313|EMBL:EKF39291.1};
GN ORFNames=MOQ_000486 {ECO:0000313|EMBL:EKF39291.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF39291.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF39291.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF39291.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF39291.1}.
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DR EMBL; AHKC01001403; EKF39291.1; -; Genomic_DNA.
DR AlphaFoldDB; K2NW65; -.
DR EnsemblProtists; EKF39291; EKF39291; MOQ_000486.
DR OrthoDB; 154453at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR045199; ATAD2-like.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23069; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23069:SF0; TAT-BINDING HOMOLOG 7; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117};
KW Reference proteome {ECO:0000313|Proteomes:UP000007350}.
FT DOMAIN 167..309
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 94..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 911..942
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..967
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1068 AA; 121083 MW; 935DA052759F687D CRC64;
MSHYVKGLMD WEKMRMKNCF VNHSSSLSSA EGFMSEGESR RVFRKAKEST VKHIPINHYL
NEVMKASQNN AKKGDKRKGK SHRRRMEDMF LGLNEAHGSP ADTGKGGERQ PVTETSAPLG
DITPLHIDTS VSFEKVGGLP GHIVMLREMV LFPLLYPHLL QTMNLTPPRG VLFVGPPGTG
KTLMARALAN EAASCAQRKI AFFMRKGADI LSKWVGESER QLSLLFEEAR RRQPSIIFFD
EIDGLVPVRH AKAEQSQAAL VSTLLALIDG LDDRGQVIVI GATNRPDTID PALRRPGRLD
RELYFPLPDA AARRHILSIV TQPILSLDHP ERNAIMEELA IRCEGWSGAE IQALCTEAGL
NRLRTSLPQL YVTSRKLQIP NNALTIQKED FFVAAHRFKT SVRRGTESIV KGLEEHLEHL
LYSTRMKLVS SVASMWPSAA TALASERRDC SNASDAVREL SGFPIPHTVK PMLLFLTSSI
ERNLYGVESY EFALEKAALA FIKALPSIRI FTLNLPNLVV DRGSAPMMVT ATGSAMPEGS
AGNFEELGFP LNNSFTSGHI YSCIMAIQRS SGPSLVLLQG LDLWLSEYGY PINNDEGNED
DRADEERTQQ KKQMESFCYY LALLRDSDVL IVAPTLHCDV LSRFFGGTRL NAQINKTLCN
VPCAPSDDDL QRFLQYVFHV VELALLHCTH TVWEELNEDV SPPPPPSMEE VRAARHGTLE
LWRRVEYRRR QLRYVLSKWL GQYLASRKFS ILCSADLDFT PSHDLYDEWR QHTQGRRIGL
CDVMEKLENE EYTSLSQYHD DIDMLVRNVR TFFRTRSSTD QRYRSRALEL KETTVLNLYK
INRNVVQFCE QYKDLAEPDV SLSSHSSNLN VKPKIKEPTE PRAVQITVKR KRTPHRYYVG
RRRRRYNFRK KRKVREDDNL HKIEDENGEE TTREEGRSAN GDELKTEPAA PEAVPRDEKD
VDDHTVSVER NGSNSLDFSS SVAQCDKATE IRVSMEMLRG LSFLELHGVF QAAMSLLEEE
VSRRRNQQQN VSVSPLTGTT EVGNNSFFLW MLKEAVRTAV KERRGRSD
//
