ID K2RYU7_MACPH Unreviewed; 1116 AA.
AC K2RYU7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Structural maintenance of chromosomes protein 5 {ECO:0000256|ARBA:ARBA00018687};
GN ORFNames=MPH_04846 {ECO:0000313|EMBL:EKG17897.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG17897.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG17897.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG17897.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC5 subfamily.
CC {ECO:0000256|ARBA:ARBA00010171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG17897.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHHD01000221; EKG17897.1; -; Genomic_DNA.
DR AlphaFoldDB; K2RYU7; -.
DR STRING; 1126212.K2RYU7; -.
DR VEuPathDB; FungiDB:MPH_04846; -.
DR eggNOG; KOG0979; Eukaryota.
DR HOGENOM; CLU_004969_2_0_1; -.
DR InParanoid; K2RYU7; -.
DR OrthoDB; 232016at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR027131; SMC5.
DR PANTHER; PTHR45916; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR PANTHER; PTHR45916:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 74..1069
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 236..326
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 420..482
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 681..774
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 810..945
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1116 AA; 129472 MW; D4025CE2758D0569 CRC64;
MARIRHSSEV EDDDSGEDSY LSQSRRPAKR PRVEDDVSEA SNEPVLPDSY RSQPRHDASS
SNEHTPLKHQ PGSIVRVKLT NFVTYTSAEF LLGPSLNMII GPNGTGKSTL VCAICLGLGW
GPQHLGRAKE LGEFVKHGAR EAEIEIELSK GPKHQRNPVI RRTIRREGNK TSFTLNGQQT
THKQITALCK SFAIQIDNLC QFLPQDRVVE FAALNPVQLL EQTQRAAAPD YMNEWHEQLK
ELRKEQKLKM DARNRENETL RDLQNRHNLQ RADVERMQER QALTDKMYAY TRLRPFVHYR
TAKERYDASN QACKDAQHEL RQLQQREQPA IDALEDKRNY HKQVEQVAGK RARLLQRMER
TAEGIRQEMG ELQTQIDDKE NERTAEKNSN KERARQRDKL VRDIKIIEER MKERPPDFDA
AAYNERAREK QRAARELQTQ NHDSIQQQRE IVNQIRTLEA QKQQVQTEIE NLKSQAGQRS
NKLKGLSADT WRAWDWIQKN RDQLTGEVFG PPVVSCSVND NRFANAVESM FQRGDLLAFT
VTNRRDFGVL SRTFRNMNLK DIHIKEASRP RESWRPIMPT DELGQLNLSG FLIDCLSGPD
PVLSSLCDSL RLHQCAVSLQ DHNDEQFERI KRSSIQRWVA GRSSYQVTRR REYGDQAVST
IVRQVNPARI WTDQPVDIGA EREHQAKIRD LNHDIEEFTN QGRELSAQIQ TNKEQIQQLG
REKDEIDKEK HDLQKIRGEF EGLQTKKDTC EFRLQELQAE LRDTAERVEN IDVATDDLVL
RKGQLAIDYA NSVRGLLDLH QEVYEAEIVL AEAKSELQVS EERSQDIRRE IAVHQENIRG
LKAEKERLKK EAERMRDEVN RINNERSEEE EALVENIQAT ISLEDLEAEI TAFESRLKLL
HGGDPNAIRD FERRARRIEE LERRLEELDK ELEELQGRIE EIKSRWEPEL DALVQNISDA
FSFNFSKIGC AGQVSIYKAE DFSDWAIQIQ VKFREQEQLS ILDSHRQSGG ERAVSTIFYL
MALQSLARSP FRVVDEINQG MDPRNERMVH ERMVDIACQE HTSQYFLITP KLLHGLKFHP
RMTVHCIASG EYMPIDYREL DFKTLVDVAL RVKGRA
//
