ID K3V196_FUSPC Unreviewed; 519 AA.
AC K3V196;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=FPSE_00833 {ECO:0000313|EMBL:EKJ78976.1};
OS Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ78976.1, ECO:0000313|Proteomes:UP000007978};
RN [1] {ECO:0000313|EMBL:EKJ78976.1, ECO:0000313|Proteomes:UP000007978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS3096 {ECO:0000313|EMBL:EKJ78976.1,
RC ECO:0000313|Proteomes:UP000007978};
RX PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT "Comparative pathogenomics reveals horizontally acquired novel virulence
RT genes in fungi infecting cereal hosts.";
RL PLoS Pathog. 8:E1002952-E1002952(2012).
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ78976.1}.
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DR EMBL; AFNW01000016; EKJ78976.1; -; Genomic_DNA.
DR RefSeq; XP_009252228.1; XM_009253953.1.
DR AlphaFoldDB; K3V196; -.
DR EnsemblFungi; EKJ78976; EKJ78976; FPSE_00833.
DR GeneID; 20359453; -.
DR KEGG; fpu:FPSE_00833; -.
DR eggNOG; KOG1369; Eukaryota.
DR HOGENOM; CLU_014393_4_0_1; -.
DR OrthoDB; 5481886at2759; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000007978; Chromosome 4.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR InterPro; IPR022672; Hexokinase_N.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR PANTHER; PTHR19443:SF29; PHOSPHOTRANSFERASE; 1.
DR Pfam; PF00349; Hexokinase_1; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362007};
KW Reference proteome {ECO:0000313|Proteomes:UP000007978};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 7..229
FT /note="Hexokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00349"
FT DOMAIN 243..509
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 519 AA; 56438 MW; 060D255CA7170C17 CRC64;
MTSSLSIEEF LEPLSVDIDK IEQLSQNFLE TFEKLASDSE NQFLPTPISG AILRPEAKRR
QGCHLAIDIG GTNLRVGFVQ LGNDASSATS DQLNGHVGNG PDEGATTRQV RRRLEKSWPI
DEHLKNENPD SLFQWIGQCI AEVVQDGCKT LQLQADQPMP LGVTFSFPMV QHSISQATLM
PMGKGFAISS DQDLGGRLTD GYNRAKSPDL PPIRVEAIAN DSVSTLVSFI FNFHEASNRR
ACMGLILGTG CNATIPLKLS QLSPSKRPPS VVARPEERAE DVNIAINTEW SINGTAPPLY
DVGLVTRWDR ALDQQGELNS FQPLEYLTSG RYLGELGRLM LVDYLTEHLG IAAGTLPKAL
LQRHNLTTTY LSHFKPLQPS TLMTSLQQEF PESSGSPPFG WTEEIATALY RIAKAIEVRA
AGIVAAATLA LLTLAGDVPR DGAHALDRDC ELGVGYTGGC IVHFQDYLQD CQDFLDELLS
KRFGDESPLR VVLSPCHDGG VTGAGILVAA ASQSRTIKN
//
