ID K3VKQ6_FUSPC Unreviewed; 542 AA.
AC K3VKQ6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=FPSE_04375 {ECO:0000313|EMBL:EKJ75422.1};
OS Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ75422.1, ECO:0000313|Proteomes:UP000007978};
RN [1] {ECO:0000313|EMBL:EKJ75422.1, ECO:0000313|Proteomes:UP000007978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS3096 {ECO:0000313|EMBL:EKJ75422.1,
RC ECO:0000313|Proteomes:UP000007978};
RX PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT "Comparative pathogenomics reveals horizontally acquired novel virulence
RT genes in fungi infecting cereal hosts.";
RL PLoS Pathog. 8:E1002952-E1002952(2012).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ75422.1}.
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DR EMBL; AFNW01000087; EKJ75422.1; -; Genomic_DNA.
DR RefSeq; XP_009255768.1; XM_009257493.1.
DR AlphaFoldDB; K3VKQ6; -.
DR EnsemblFungi; EKJ75422; EKJ75422; FPSE_04375.
DR GeneID; 20362993; -.
DR KEGG; fpu:FPSE_04375; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_026673_16_5_1; -.
DR OrthoDB; 2688376at2759; -.
DR Proteomes; UP000007978; Chromosome 4.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR Pfam; PF08240; ADH_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007978}.
FT DOMAIN 15..301
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 542 AA; 59622 MW; 8E86EAA473E0411C CRC64;
MELSNKAAYL ISPNGPTIEV RSAPVPTPGQ GELLVKTHAV AINPVDAVKQ SMGNMMFEWL
KYPLILGYDV AGEVIKTGPG VSRFKEGDRV VGVTAGMDKR GRCPDEGAFQ ELCIIREHLA
AKIPDGITFT DASVLPLTFV TAACALFQKE QLALQPPQTK AKRSSTGQTV LVWGASTSVG
RNAVQLAVAA GYDVIATASP KNWDIVRGLG VCAVFDYRSP SVINDVITSF KDKRCAGAVA
IGQGSLAKCV DIIKRIPGAT KNVAQVTLSM PESQPTTKLS MIPFVAKYFW MAGTDRLKVV
TSGVQSKFVF GTDIIEWDPE GKMASFLTEG LELGQYKLSS EAQVLEGGLS SITQGLDLVR
GDTGAKLKQD FRRKGKQADI ISFTLLMMAN YASLGTTYSS SVYSLLARIN HLSEIVWHMP
YDFPVLDRAQ REMGLVILPF NLPSREFMHL LDEDLSEVSF EMDVFLSHLS DEENPGLRDY
LVQKFESVES ACDRIYMVVL ELDPVRRDEA LNELAEAHDF QSISLESLVP CEDRVYYLWW
MM
//
