ID K3VQT5_FUSPC Unreviewed; 537 AA.
AC K3VQT5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein {ECO:0000259|Pfam:PF17851};
GN ORFNames=FPSE_02502 {ECO:0000313|EMBL:EKJ77424.1};
OS Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ77424.1, ECO:0000313|Proteomes:UP000007978};
RN [1] {ECO:0000313|EMBL:EKJ77424.1, ECO:0000313|Proteomes:UP000007978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS3096 {ECO:0000313|EMBL:EKJ77424.1,
RC ECO:0000313|Proteomes:UP000007978};
RX PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT "Comparative pathogenomics reveals horizontally acquired novel virulence
RT genes in fungi infecting cereal hosts.";
RL PLoS Pathog. 8:E1002952-E1002952(2012).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ77424.1}.
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DR EMBL; AFNW01000059; EKJ77424.1; -; Genomic_DNA.
DR RefSeq; XP_009253896.1; XM_009255621.1.
DR AlphaFoldDB; K3VQT5; -.
DR EnsemblFungi; EKJ77424; EKJ77424; FPSE_02502.
DR GeneID; 20361121; -.
DR KEGG; fpu:FPSE_02502; -.
DR eggNOG; ENOG502SM8A; Eukaryota.
DR HOGENOM; CLU_016508_2_1_1; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000007978; Chromosome 3.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd09000; GH43_SXA-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000007978}.
FT DOMAIN 327..526
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 15
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 187
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 128
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 537 AA; 61354 MW; BD59D5ACE68596B8 CRC64;
MPRVRNPILP GFNPDPSIVR VGDDYYIATS TFEWFPGVQI HHSRDLANWT LVVRPLTRKN
QLDMRGEPDS CGVWAPCLSH DGEKFWLVYT DVKRKDGSFK DAHNYIVTAT SIEGPWSDPV
YANSSGFDPS LFHDDDGKKW FNNMTWDHRS RPRTFEGIFL QEFDPKANKL VGPRKNIFEG
TDLAFVEGSH IYKRNGWYYL STAEGGTGYT HAITLARSRN VWGPYEVHPQ KYILTSKDTP
HAALQRAGHG QIVETPDGKT YVVHLTGRPT TQKRRSVLGR ETAIQEAYWG DDEWLYIKNG
PVPSLYVDLP AERDDTVYWE EKRYTFKDTL HSDFQWLRTP EPERIFNIKD GQLTLIGRES
IGSWFEQALV ARRQTHFSYD AETVIDFSPE DERQFAGLTA YYCRFNFFYL TVTAHADGQR
ELLILSSEET FPLGRLNKPL AESVKIPNEG KVKLALTIRG NKLQFFYALE GKELTKIGPV
YDASLLSDEC GGHPNDGSFT GAFVGMAASD VNGLAMEAKF DYFVYRPVHD DSDRYDI
//
