ID K3XVL6_SETIT Unreviewed; 696 AA.
AC K3XVL6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN Name=101762443 {ECO:0000313|EnsemblPlants:KQL10027};
GN ORFNames=SETIT_4G099200v2 {ECO:0000313|EMBL:RCV20948.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL10027, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV20948.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL10027,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV20948.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV20948.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV20948.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL10027}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL10027};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: Probable ATP-dependent zinc metallopeptidase.
CC {ECO:0000256|ARBA:ARBA00003497}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|RuleBase:RU003651}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR EMBL; AGNK02002305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003531; RCV20948.1; -; Genomic_DNA.
DR RefSeq; XP_004965045.1; XM_004964988.1.
DR AlphaFoldDB; K3XVL6; -.
DR STRING; 4555.K3XVL6; -.
DR MEROPS; M41.019; -.
DR EnsemblPlants; KQL10027; KQL10027; SETIT_005974mg.
DR GeneID; 101762443; -.
DR Gramene; KQL10027; KQL10027; SETIT_005974mg.
DR KEGG; sita:101762443; -.
DR eggNOG; KOG0731; Eukaryota.
DR HOGENOM; CLU_000688_16_2_1; -.
DR InParanoid; K3XVL6; -.
DR OMA; KYDSDPM; -.
DR OrthoDB; 94at2759; -.
DR Proteomes; UP000004995; Chromosome IV.
DR GO; GO:0009534; C:chloroplast thylakoid; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:GO_Central.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.720.210; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR InterPro; IPR006311; TAT_signal.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF118; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 6, CHLOROPLASTIC; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003651};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003651}; Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 266..405
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 74424 MW; 85606851051A5D95 CRC64;
MSRTAMSLTM TSRLPICRAQ DVSKQASPQQ QKRAPPSAKA TPPSTPDATG GLNRRRLLQS
AGLGLGLGLA AGDPARARAE TAAAAPPPAL APEDPTSNRM SYSRFLDYLD AGAVRKVDFF
ENGTVAVVEL DDPALASRTH RVRVQLPGLP PELLRKLRDR GVDFAAHPVE PNPGLVLLDF
LLNFGFPLLF VATLIWRSVT INNPGAGGGP NLPFGLGKSK AKFQMEPNTG ITFDDVAGVD
EAKQDFQEIV QFLKSPEKFA ALGARIPKGV LLVGPPGTGK TLLAKAIAGE AGVPFFSLSG
SEFIEMFVGV GASRVRDLFN KAKENAPCLV FIDEVDAVGR QRGTGIGGGN DEREQTLNQL
LTEMDGFAGD SGVIVIAATN RPEILDAALL RPGRFDRQVS VGLPDVRGRE EILRVHSSNK
KLDPDVSLSV VAMRTPGFSG ADLANLMNEA AILAGRRGKD RITVKEIDDS IDRIVAGLEG
TSMTDGKSKM LVAYHEIGHA VCATLTPGHD EVQKVTLIPR GQARGLTWFL PGEDPTLVPK
QQIFARIVGG LGGRAAEEVI FGEPEVTTGA AGDLQQVTQV ARQMVTTFGM SEIGPWALVE
PAAQSGDVVM RMLARNSMSE KLAADIDAAV KRIVDQAYEV AKEHVRRNRA AIDQLVDVLM
EKETLSGDEF RAILSEHVDI GKEQRETAAR TELVTA
//
