ID K3Z372_SETIT Unreviewed; 1298 AA.
AC K3Z372;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=101764444 {ECO:0000313|EnsemblPlants:KQL16960};
GN ORFNames=SETIT_3G367600v2 {ECO:0000313|EMBL:RCV19228.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL16960, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV19228.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL16960,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV19228.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV19228.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV19228.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL16960}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL16960};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNK02002096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003530; RCV19228.1; -; Genomic_DNA.
DR RefSeq; XP_004963004.1; XM_004962947.2.
DR RefSeq; XP_004963005.1; XM_004962948.2.
DR STRING; 4555.K3Z372; -.
DR EnsemblPlants; KQL16959; KQL16959; SETIT_020990mg.
DR EnsemblPlants; KQL16960; KQL16960; SETIT_020990mg.
DR GeneID; 101764444; -.
DR Gramene; KQL16959; KQL16959; SETIT_020990mg.
DR Gramene; KQL16960; KQL16960; SETIT_020990mg.
DR KEGG; sita:101764444; -.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_8_8_1; -.
DR InParanoid; K3Z372; -.
DR OMA; KHLWLEC; -.
DR OrthoDB; 372655at2759; -.
DR Proteomes; UP000004995; Chromosome III.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1045; OS12G0205000 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 18..104
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 223..454
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1298 AA; 146711 MW; DED0C02940F8D5F6 CRC64;
MAPAAALVFA GKSVAIPAIS FLVNKAFAYL NQYWKTEGID EMKSRILLAL PKIRAVFDVV
NPERIKEESI ALDAWLWHLR DAVEKAEDAV DEIEYYELKE KAKDLKVSDW GSSFAKMKHS
AIKSVKHASI VDKAVKGLSH RGTLRRLQKA LEGLDKAAAG VVGFLALADH LGGSTSRQEE
DSLNKDRETG SMIIATKVFG RRKESEEVIG WLTKPSVGDA EIEVSKVSVV SIVGHGGMGK
TTLAQLIHND DTIKRHFDKV IWACVSTTFN ATTVIRNILE NATWPTNGAS TLDALQKILR
EKVDSLKFLV ILDDVWEDKT DDQWGKLFAP LRGGKNGSKI LLTTRMKGVA EMADQVMRGE
NKLLELQGLD EDDNIELFSH HAFPSCGLQD DAALKRTGEQ IAKNLRGCPL VTKVVGAHLR
DNMRLDYWNE FLTQSLKHFY GGSEDIMDVL KLSYYHLPPV LQTCFRFCSL FPQDYEFGKD
QLVEMWVDSG LISQDAFGTQ SLVDVGENYL VQLTRKSFFD LRFRVDPFGQ EDRESGYYVM
HDLMHDLATN VSFGECLRMV DGGSLENVPS TVRHVRVAYI HNFPMEKMKK ISCLENLRTI
IIVKGIPWSV EENIDILNTV EELVESSKSL RLFQTHLRHR SHFASKLAKL KHLRCIILAD
TRMTQESMSG VFKLYHLRKL IWRSTKIGSK QVRDVGYLDR LQYVSYKPFG GSGCSMVPVA
RLTSLRVLEN YHITRIKGYN MSALKDLGSL RSLSVDTLEN VDNQEEAKKA KMKEKKCLES
LRLEWTGCNG VRSRTHELIL DSLEPHANLK KLCISGFRGS RIPHWIAEPR VENLVKLDFN
FCEHIEELTS LGKLLKLKDL TLSGLISLRR IGQPSNASGD GRMELFLPPS LQKLYIQQCL
KLEELPLLPP SLVRLDIQEV GLIRLPRIVK LHSSTDESIS SKWLDIMVRS CQRLTSLEGS
LFEQKQCIQV IREMSIINCM HLESAPFPFE ETNELRKIHI ENCPELRLLS GAEDKLPLPS
LKTLAMGWCG DLELLLLESL QVFTNLSNLS LRNCSVVESL PSADVFANLT SLRIISLIGC
RNLSSLGGLR SLPRLEDLEI VNCSKLAEAG LSLTFGVSGC EEERGSFKQI KSIMIDHPAL
LLVEPVRSLC PTYRLQIRDG SEMLDAIEPW LLRNCTSLQY LWISKVNLES LPLSISELSS
LETLRLYNSD QLRSLPNVPS SLHTLHIYSC HSELRKKASE RGSLEWNKIC HIPYVFIGGY
YFRKGEGISE ESFFQGIWEQ GLMMLELKRR EAINQLVF
//
