ID K3Z5W8_SETIT Unreviewed; 475 AA.
AC K3Z5W8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=Aspartyl aminopeptidase {ECO:0008006|Google:ProtNLM};
GN Name=101784674 {ECO:0000313|EnsemblPlants:KQL13650};
GN ORFNames=SETIT_3G089700v2 {ECO:0000313|EMBL:RCV15834.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL13650, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV15834.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL13650,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV15834.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV15834.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV15834.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL13650}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL13650};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M18 family.
CC {ECO:0000256|ARBA:ARBA00008290, ECO:0000256|RuleBase:RU004386}.
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DR EMBL; AGNK02001469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003530; RCV15834.1; -; Genomic_DNA.
DR RefSeq; XP_004960722.1; XM_004960665.2.
DR AlphaFoldDB; K3Z5W8; -.
DR STRING; 4555.K3Z5W8; -.
DR MEROPS; M18.A01; -.
DR EnsemblPlants; KQL13650; KQL13650; SETIT_021936mg.
DR GeneID; 101784674; -.
DR Gramene; KQL13650; KQL13650; SETIT_021936mg.
DR KEGG; sita:101784674; -.
DR eggNOG; KOG2596; Eukaryota.
DR HOGENOM; CLU_019532_2_0_1; -.
DR InParanoid; K3Z5W8; -.
DR OMA; GPILKVN; -.
DR OrthoDB; 1156at2759; -.
DR Proteomes; UP000004995; Chromosome III.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05658; M18_DAP; 1.
DR Gene3D; 2.30.250.10; Aminopeptidase i, Domain 2; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR001948; Peptidase_M18.
DR InterPro; IPR023358; Peptidase_M18_dom2.
DR PANTHER; PTHR28570; ASPARTYL AMINOPEPTIDASE; 1.
DR PANTHER; PTHR28570:SF16; ASPARTYL AMINOPEPTIDASE-RELATED; 1.
DR Pfam; PF02127; Peptidase_M18; 1.
DR PRINTS; PR00932; AMINO1PTASE.
DR SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000256|RuleBase:RU004386};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004386};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004386};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU004386};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004386};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004386}.
SQ SEQUENCE 475 AA; 52293 MW; 3A3BE17E37B84A71 CRC64;
MASVAPVVSD LVDFLNASPT AFHAVDEAKR RLKAAGFAQL SEREEWAGLE PGRKYFFTRN
YSTIVAFAIG AKYVAGNGFH IIGAHTDSPC LKLKPVSKVT KGGYLEVGVQ TYGGGLWYTW
FDRDLTVAGR VIIREKRDGG DSCAHKLVRV QEPILRIPTL AIHLDRTISS EGLKINNQNH
LVPVLATSIK NEMQKLVGEN GPKESSENKN TKHHPLLLQL IAKEANCEPD EICDFELQLC
DTQPSAVAGA MKEFIFSGRL DNLCMSFCSL KALIDSTSAE HSLDHESGVR MVALFDHEEV
GSDSAQGAGS PAMLDALSRI TGSFNSSNSK LLEKAIQRSF LVSADMAHAL HPNYMDKHEE
NHQPKLHGGL VIKHNANQRY ATNAVTAFIF REIAERHQLP VQDFVVRNDM ACGSTIGPIL
ASGVGIRTVD IGAPQLSMHS IREMCAVDDI SHSYEHFKAY FEEFTELDSK VKVDY
//
