ID K3ZMX2_SETIT Unreviewed; 407 AA.
AC K3ZMX2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Chalcone/stilbene synthase N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=101754841 {ECO:0000313|EnsemblPlants:KQK94798};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQK94798, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQK94798, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK94798,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQK94798}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK94798};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNK02004997; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004980567.1; XM_004980510.1.
DR AlphaFoldDB; K3ZMX2; -.
DR STRING; 4555.K3ZMX2; -.
DR EnsemblPlants; KQK94798; KQK94798; SETIT_027944mg.
DR GeneID; 101754841; -.
DR Gramene; KQK94798; KQK94798; SETIT_027944mg.
DR KEGG; sita:101754841; -.
DR eggNOG; ENOG502S4A6; Eukaryota.
DR HOGENOM; CLU_034992_2_0_1; -.
DR InParanoid; K3ZMX2; -.
DR OMA; AGARECC; -.
DR OrthoDB; 5534222at2759; -.
DR Proteomes; UP000004995; Chromosome VIII.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProt.
DR GO; GO:0030639; P:polyketide biosynthetic process; IBA:GO_Central.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF102; CHALCONE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 15..228
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 239..391
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 165
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 407 AA; 43710 MW; DE279E29E5C2E0A3 CRC64;
MASHPVDVDK IRHGQRAAVL AIGTANPMNC VRQDEYADWY FRATGSDHLP HLKAKMKRMC
DRSGIRKRYF HHSERMIREH PALLGRDELP SLNARQDILA AAVPELAAAA AEDAIAEWGR
PASDVTHLVV CTYSGAHMPG ADLRLASLLG LRPTVCRTVL YLQGCTAGSA ALRVAKDVAE
NNRGARVLVA CAELTLVMLR APDEARPGTL VMQSMFGDGA SAAVVGAEAE EPVERPLFEM
VSAYQDVIPE TTDSRAAGQL NEDGLVFQPS SGMPALVRQN IERCVADALA PLGLRGGGGG
WNELFWAVQP SGRAILDGVE AGLALEPEKL AASRRVLREY GYMSGASMLF VLDELRRRHV
GGGWDDMPAG GMGVMVGIGP GISVETMVLR AANSSQSRNG VLRSPWQ
//
