ID   K4EKQ4_9RODE            Unreviewed;       159 AA.
AC   K4EKQ4;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=von Willebrand factor {ECO:0000256|ARBA:ARBA00016619};
DE   Flags: Fragment;
GN   Name=vWF {ECO:0000313|EMBL:AEK81897.1};
OS   Orientallactaga sibirica (Mongolian five-toed jerboa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Dipodoidea;
OC   Dipodidae; Allactaginae; Orientallactaga.
OX   NCBI_TaxID=234626 {ECO:0000313|EMBL:AEK81897.1};
RN   [1] {ECO:0000313|EMBL:AEK81897.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=As {ECO:0000313|EMBL:AEK81897.1};
RX   PubMed=23071573; DOI=10.1371/journal.pone.0046445;
RA   Wu S., Wu W., Zhang F., Ye J., Ni X., Sun J., Edwards S.V., Meng J.,
RA   Organ C.L.;
RT   "Molecular and paleontological evidence for a post-cretaceous origin of
RT   rodents.";
RL   PLoS ONE 7:E46445-E46445(2012).
CC   -!- SUBUNIT: Multimeric. Interacts with F8.
CC       {ECO:0000256|ARBA:ARBA00025858}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   EMBL; JF938694; AEK81897.1; -; Genomic_DNA.
DR   AlphaFoldDB; K4EKQ4; -.
DR   GO; GO:0031012; C:extracellular matrix; IEA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   CDD; cd01450; vWFA_subfamily_ECM; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR032361; VWA_N2.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR22588:SF5; COLLAGEN ALPHA-6(VI) CHAIN; 1.
DR   PANTHER; PTHR22588; UNCHARACTERIZED; 1.
DR   Pfam; PF00092; VWA; 1.
DR   Pfam; PF16164; VWA_N2; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          32..159
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEK81897.1"
FT   NON_TER         159
FT                   /evidence="ECO:0000313|EMBL:AEK81897.1"
SQ   SEQUENCE   159 AA;  18064 MW;  7E7CB5F98897B270 CRC64;
     WCTDVPISPT TLYVEDTPEP PLHAFYCSKL LDLVFLLDGS SQLSEAEFEV LKAFVVGMME
     RLHISQKRIR VAVVEYHDGS HAYIELKARK RPSELRQIAS HVKYAGSQVA STSEVLKYTL
     FQIFGNIDRP EASRITLLLT ASQEPPRMVR NLVRYVQGL
//