ID K4GCY0_CALMI Unreviewed; 229 AA.
AC K4GCY0;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE RecName: Full=Pentraxin family member {ECO:0000256|RuleBase:RU362112};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFM90596.1};
RN [1] {ECO:0000313|EMBL:AFM90596.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AFM90596.1};
RX PubMed=23056606;
RA Tan Y.Y., Kodzius R., Tay B.H., Tay A., Brenner S., Venkatesh B.;
RT "Sequencing and Analysis of Full-Length cDNAs, 5'-ESTs and 3'-ESTs from a
RT Cartilaginous Fish, the Elephant Shark (Callorhinchus milii).";
RL PLoS ONE 7:E47174-E47174(2012).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|RuleBase:RU362112};
CC Note=Binds 2 calcium ions per subunit. {ECO:0000256|RuleBase:RU362112};
CC -!- SUBUNIT: Homopentamer. Pentaxin (or pentraxin) have a discoid
CC arrangement of 5 non-covalently bound subunits.
CC {ECO:0000256|RuleBase:RU362112}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362112}.
CC -!- SIMILARITY: Belongs to the pentraxin family.
CC {ECO:0000256|RuleBase:RU362112}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
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DR EMBL; JX212282; AFM90596.1; -; mRNA.
DR AlphaFoldDB; K4GCY0; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001759; Pentraxin-related.
DR PANTHER; PTHR45869:SF8; -; 1.
DR PANTHER; PTHR45869; C-REACTIVE PROTEIN-RELATED; 1.
DR Pfam; PF00354; Pentaxin; 1.
DR PRINTS; PR00895; PENTAXIN.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51828; PTX_2; 1.
PE 2: Evidence at transcript level;
KW Calcium {ECO:0000256|RuleBase:RU362112};
KW Metal-binding {ECO:0000256|RuleBase:RU362112};
KW Signal {ECO:0000256|RuleBase:RU362112}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|RuleBase:RU362112"
FT CHAIN 20..229
FT /note="Pentraxin family member"
FT /evidence="ECO:0000256|RuleBase:RU362112"
FT /id="PRO_5006992883"
SQ SEQUENCE 229 AA; 25083 MW; 0752056CB0336A26 CRC64;
MKSLLLIVAS CLLSGLASAD EDRQGLIGES LIFSTPSDTN HVLLTPSRDM DLKNFTLCLR
VNTESPRQHV LFSYATQSSP SELLLKREDE TTVSLTVSGV KIPFLVRSSQ LSSWVHVCAR
RDMMAKQVIL HINGRPSVRK ALEPSNPIKP GGKVVLGQEQ GGVGGGFQQE KCLVGEIADV
HLWDHILTTS TIRAISMGDP IYRGNVIDWL TVKHTIKGQV KSLRTTSVN
//
