ID K4KYA1_9FIRM Unreviewed; 430 AA.
AC K4KYA1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:AFV04195.1};
GN ORFNames=DCF50_p189 {ECO:0000313|EMBL:AFV04195.1};
OS Dehalobacter sp. CF.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Dehalobacter.
OX NCBI_TaxID=1131462 {ECO:0000313|EMBL:AFV04195.1, ECO:0000313|Proteomes:UP000000482};
RN [1] {ECO:0000313|EMBL:AFV04195.1, ECO:0000313|Proteomes:UP000000482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AFV04195.1};
RX PubMed=23284863; DOI=10.1371/journal.pone.0052038;
RA Tang S., Gong Y., Edwards E.A.;
RT "Semi-automatic in silico gap closure enabled de novo assembly of two
RT dehalobacter genomes from metagenomic data.";
RL PLoS ONE 7:E52038-E52038(2012).
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DR EMBL; CP003870; AFV04195.1; -; Genomic_DNA.
DR AlphaFoldDB; K4KYA1; -.
DR STRING; 1131462.DCF50_p189; -.
DR KEGG; dec:DCF50_p189; -.
DR PATRIC; fig|1131462.4.peg.195; -.
DR eggNOG; COG0535; Bacteria.
DR HOGENOM; CLU_009273_1_1_9; -.
DR Proteomes; UP000000482; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21121; SPASM_Cmo-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR027604; W_rSAM_matur.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SFLD; SFLDF00570; tungsten_cofactor_oxidoreducas; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000482};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 64..297
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 430 AA; 47820 MW; FD6AB7C70756E06F CRC64;
MCGCGSSSRE RKKTKEGTIK QETQINPDGS LPLSEEVLEQ LGITAGSKVI VSSSPSGLSL
RNINPALSKI YIEPTNTCNL NCRTCIRHTW KDPVGFLKME TYIKLLEEVS TIPSITKISF
WGFGEPLLHP NIVEMIARAK TLGLETQLIT NGLLLDLKMA KSLVAANLDS IVVSIDGSSE
ETQADVRSGA DLNLVKKNIK QLRLVRYHNE SATPEIGIEF VAMKSNVKEL GNIKDVACEL
GANFIFVTNV LPYSSELKDE ILYWQSVDMK LPQQGCEFMP KITFPPMDNR REEVGENLFK
ISGPVDLSHT IVNKGDGYCR FVGEGSLVIS WDGEVSPCAA LMHAYSCYVL GRKKDIKRYT
VGNIEQDNIT DLWDNQDFTN FRERVQRFDF APCTHCGGCE MAESNEEDCY DNTFPVCGDC
LWAQGVIQCP
//
