ID K4L532_9FIRM Unreviewed; 445 AA.
AC K4L532;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative reductive dehalogenase subunit A {ECO:0000313|EMBL:AFV06387.1};
GN Name=rdhA {ECO:0000313|EMBL:AFV06387.1};
GN ORFNames=DCF50_p2384 {ECO:0000313|EMBL:AFV06387.1};
OS Dehalobacter sp. CF.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Dehalobacter.
OX NCBI_TaxID=1131462 {ECO:0000313|EMBL:AFV06387.1, ECO:0000313|Proteomes:UP000000482};
RN [1] {ECO:0000313|EMBL:AFV06387.1, ECO:0000313|Proteomes:UP000000482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AFV06387.1};
RX PubMed=23284863; DOI=10.1371/journal.pone.0052038;
RA Tang S., Gong Y., Edwards E.A.;
RT "Semi-automatic in silico gap closure enabled de novo assembly of two
RT dehalobacter genomes from metagenomic data.";
RL PLoS ONE 7:E52038-E52038(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- COFACTOR:
CC Name=corrinoid; Xref=ChEBI:CHEBI:33913;
CC Evidence={ECO:0000256|ARBA:ARBA00029374};
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DR EMBL; CP003870; AFV06387.1; -; Genomic_DNA.
DR RefSeq; WP_015044418.1; NC_018867.1.
DR AlphaFoldDB; K4L532; -.
DR STRING; 1131462.DCF50_p2384; -.
DR KEGG; dec:DCF50_p2384; -.
DR PATRIC; fig|1131462.4.peg.2403; -.
DR eggNOG; COG1600; Bacteria.
DR HOGENOM; CLU_036586_0_0_9; -.
DR Proteomes; UP000000482; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR012832; RDH.
DR InterPro; IPR028894; RDH_dom.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR019546; TAT_signal_bac_arc.
DR NCBIfam; TIGR02486; RDH; 1.
DR NCBIfam; TIGR01409; TAT_signal_seq; 1.
DR PANTHER; PTHR42827:SF1; IRON-SULFUR CLUSTER BINDING PROTEIN; 1.
DR PANTHER; PTHR42827; IRON-SULFUR CLUSTER-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF13486; Dehalogenase; 1.
DR Pfam; PF13484; Fer4_16; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000482};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 324..354
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 445 AA; 48750 MW; A3BC51F978D99B4D CRC64;
MDLGNEKTKS TTQESTKQEK ALSQKFSRRG FLKTSIGIGA GAAGAALLGY DGSIANAAEV
VQHDTMPVEI SSDYQRYDQK KGVIFRAMMG DPAVKTSFET YFGKHMQTIP INTGEGYGRL
EEAMVAGAWG VEDGLNGYHA PGFASQGLYE WKPSQVSGKV NPNQYKFESP EAASEAVKRA
AKFFGASLVG ITPYDERWVF SKVFDMQKLD SVPNVFPFQP TNAIILALEM DYQAFEAAPT
SLELAATGNI YSNMGVLVNK LSHFIRSLGY QTIPCGNDTA LSVPMAIQAG LGELSRIGIL
ITPEFGPRQR LCKIFTDLPL AVDKPITFGV KEFCMNCKKC TDACPSQAIS HDKEPSFVAA
TPSTNAGVKR WALNADKCLK QWGEAGTDCG VCIKVCPYNK PNEWHHDFVK LGTRTPARPV
LRFFDDLFGY GKATVTEAIK EFWKK
//
