ID K4LE10_THEPS Unreviewed; 253 AA.
AC K4LE10;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Phosphoribosylaminoimidazole carboxylase {ECO:0000313|EMBL:AFV10287.1};
DE EC=4.1.1.21 {ECO:0000313|EMBL:AFV10287.1};
GN OrderedLocusNames=Tph_c00370 {ECO:0000313|EMBL:AFV10287.1};
OS Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermacetogenium.
OX NCBI_TaxID=1089553 {ECO:0000313|EMBL:AFV10287.1, ECO:0000313|Proteomes:UP000000467};
RN [1] {ECO:0000313|EMBL:AFV10287.1, ECO:0000313|Proteomes:UP000000467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-254 / DSM 26808 / PB
RC {ECO:0000313|Proteomes:UP000000467};
RX PubMed=23259483; DOI=10.1186/1471-2164-13-723;
RA Oehler D., Poehlein A., Leimbach A., Muller N., Daniel R., Gottschalk G.,
RA Schink B.;
RT "Genome-guided analysis of physiological and morphological traits of the
RT fermentative acetate oxidizer Thermacetogenium phaeum.";
RL BMC Genomics 13:723-723(2012).
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DR EMBL; CP003732; AFV10287.1; -; Genomic_DNA.
DR RefSeq; WP_015049207.1; NZ_KI912609.1.
DR AlphaFoldDB; K4LE10; -.
DR STRING; 1089553.Tph_c00370; -.
DR KEGG; tpz:Tph_c00370; -.
DR eggNOG; COG1691; Bacteria.
DR HOGENOM; CLU_065705_0_0_9; -.
DR OrthoDB; 9782511at2; -.
DR Proteomes; UP000000467; Chromosome.
DR GO; GO:0043727; F:5-amino-4-imidazole carboxylate lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.1970; -; 1.
DR InterPro; IPR039476; P2CMN_synthase_LarB.
DR InterPro; IPR000031; PurE_dom.
DR NCBIfam; NF033503; LarB; 1.
DR PANTHER; PTHR43064; PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR43064:SF1; SLL1489 PROTEIN; 1.
DR Pfam; PF00731; AIRC; 1.
DR SMART; SM01001; AIRC; 1.
DR SUPFAM; SSF52255; N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE); 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:AFV10287.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000467}.
FT DOMAIN 119..251
FT /note="PurE"
FT /evidence="ECO:0000259|SMART:SM01001"
SQ SEQUENCE 253 AA; 27194 MW; 2737038BB1DEB4AE CRC64;
MDRSSLKKLL TDVRDGRTSV EEAFAKIRHL PYEDIGAAKI DHHRALRRGF PEVIFCQGKT
PEQALAAFRE LAGHNGRVLA TRVSPETASL IKTELPEAQY RPEARILFLS RTEIKPRWGR
IAVLSAGTSD LPVAEEAALT AELLENEVSR IYDVGVAGIH RLFSHLEELE RARVLIVVAG
MEGALPGVVA GLTDRPVIAV PTSTGYGASF GGLSALLTML NTCSPGVGVV NIDNGFGAAV
LAHLITRSGD EKP
//
