ID K5BIT3_MYCHD Unreviewed; 227 AA.
AC K5BIT3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Histidine phosphatase super family protein {ECO:0000313|EMBL:EKF21914.1};
DE SubName: Full=Phosphoserine phosphatase 2 {ECO:0000313|EMBL:VCT92746.1};
DE EC=3.1.3.3 {ECO:0000313|EMBL:VCT92746.1};
GN Name=pspB {ECO:0000313|EMBL:VCT92746.1};
GN ORFNames=C731_4129 {ECO:0000313|EMBL:EKF21914.1}, MHAS_04476
GN {ECO:0000313|EMBL:VCT92746.1};
OS Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 /
OS 3849) (Mycobacterium hassiacum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1122247 {ECO:0000313|EMBL:EKF21914.1, ECO:0000313|Proteomes:UP000006265};
RN [1] {ECO:0000313|EMBL:EKF21914.1, ECO:0000313|Proteomes:UP000006265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 {ECO:0000313|EMBL:EKF21914.1}, and DSM 44199 / CIP
RC 105218 / JCM 12690 / 3849 {ECO:0000313|Proteomes:UP000006265};
RX PubMed=23209251; DOI=10.1128/JB.01880-12;
RA Tiago I., Maranha A., Mendes V., Alarico S., Moynihan P.J., Clarke A.J.,
RA Macedo-Ribeiro S., Pereira P.J., Empadinhas N.;
RT "Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of
RT heat-stable mycobacterial proteins.";
RL J. Bacteriol. 194:7010-7011(2012).
RN [2] {ECO:0000313|EMBL:VCT92746.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mhassiacum {ECO:0000313|EMBL:VCT92746.1};
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000268660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 / CIP 105218 / JCM 12690 / 3849
RC {ECO:0000313|Proteomes:UP000268660};
RX PubMed=30701245; DOI=10.1128/mra.01522-18;
RA Sanchez M., Blesa A., Sacristan-Horcajada E., Berenguer J.;
RT "Complete genome sequence of Mycolicibacterium hassiacum DSM 44199.";
RL Microbiol. Resour. Announc. 8:e01522-e01522(2019).
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DR EMBL; AMRA01000110; EKF21914.1; -; Genomic_DNA.
DR EMBL; LR026975; VCT92746.1; -; Genomic_DNA.
DR RefSeq; WP_005631055.1; NZ_LR026975.1.
DR AlphaFoldDB; K5BIT3; -.
DR STRING; 1122247.GCA_000379865_02378; -.
DR KEGG; mhas:MHAS_04476; -.
DR PATRIC; fig|1122247.3.peg.3960; -.
DR eggNOG; COG0406; Bacteria.
DR OrthoDB; 9793115at2; -.
DR Proteomes; UP000006265; Unassembled WGS sequence.
DR Proteomes; UP000268660; Chromosome 1.
DR GO; GO:0036424; F:L-phosphoserine phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR001345; PG/BPGM_mutase_AS.
DR PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR PANTHER; PTHR48100:SF68; GLUCOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00175; PG_MUTASE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:VCT92746.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006265}.
FT ACT_SITE 10
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 83
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 9..16
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 59
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 227 AA; 24688 MW; 0538FC90C8301C01 CRC64;
MTGRLVLVRH GQSHANVERR LDTRLPGAPL TDVGRDQARG FARRLRRRPG LIAHSVAVRA
TQTADEISGH VGTEAVAVEG LHEVQVGELE DRSDDDAIAE FNAIYQRWHL GDHHVPLPGG
ESALDVLDRY LPVITELRKQ YLDHEAFTDD IVVVSHGAAI RLVSAVLAGV DAGFAIDNHL
NNAEAVVLAP TADGWNCLRW GARLPPFAPE PPVDPVQEAR QTADPMG
//
