ID K5W052_AGABU Unreviewed; 2843 AA.
AC K5W052;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=FMP27 GFWDK domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AGABI1DRAFT_73031 {ECO:0000313|EMBL:EKM80134.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM80134.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
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DR EMBL; JH971389; EKM80134.1; -; Genomic_DNA.
DR RefSeq; XP_007329011.1; XM_007328949.1.
DR STRING; 597362.K5W052; -.
DR GeneID; 18831076; -.
DR KEGG; abp:AGABI1DRAFT73031; -.
DR eggNOG; KOG1910; Eukaryota.
DR HOGENOM; CLU_000202_1_0_1; -.
DR InParanoid; K5W052; -.
DR OMA; FAHFWSW; -.
DR OrthoDB; 607689at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019443; BLTP2/FMP27/Hobbit_C.
DR InterPro; IPR019441; FMP27/BLTP2/Hobbit_GFWDK_RBG.
DR InterPro; IPR019409; FMP27_sixth_RBG.
DR InterPro; IPR019415; FMP27_SW_RBG.
DR InterPro; IPR019449; FMP27_WPPW_RBG.
DR InterPro; IPR045167; Hobbit.
DR PANTHER; PTHR15678; ANTIGEN MLAA-22-RELATED; 1.
DR PANTHER; PTHR15678:SF6; PROTEIN KIAA0100; 1.
DR Pfam; PF10293; DUF2405; 1.
DR Pfam; PF10351; FMP27-BLTP2_C; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR Pfam; PF10305; Fmp27_SW; 1.
DR Pfam; PF10359; Fmp27_WPPW; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
DR SMART; SM01215; Fmp27_SW; 1.
DR SMART; SM01216; Fmp27_WPPW; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1238..1342
FT /note="FMP27 SW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01215"
FT DOMAIN 1360..1512
FT /note="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01214"
FT DOMAIN 1749..2203
FT /note="FMP27 WPPW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01216"
FT REGION 366..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2551..2588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2562..2579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2843 AA; 318999 MW; AEA880E4678781AA CRC64;
MVQWSLSSIF STLFYILFIG NAQTLWSRNL VWLVRLIILS LLLRTYIAPW LLVLTSKHIR
IRSISLRSIK GLYFKRGRWV CRAERIGYVF RTAEGRRRLT LRVDGLKVEM QKEGEEDVKA
TRRQKRRGTL SLADLHPSPL AGHLWGIITK VTLMLEPWLR PLMRNAVVGC FRIIIKWLPA
LTQALSFELH STVFTLAQIP RTQVVADEIN LHAELILTPV ENLATVTGNN GRSTEVSPSS
SWTFYGMSTW KKKMSDGLKR ALDRAWGTMR GSASISFKLS DVVGTTPKEG QSGAFLSRIF
LRLPGSLMLD GKLKFFPQTA TIDANSVTVG LKADDIIVGV DLLNEILRVV LPTVVKRPKK
PIFAPDVPSR TLPQSSEKSE LPTVPARTPA ARHSRSPTLF SAGFLPLELS PKLPRASPLF
KAFSVSLQVA DVNMTRSSLY PRDRSFPSYK LRDCQYKSAL SSIKKVSLHV SSVSLLFSST
TSRVIDYKTL VNDVRADFHP SSAAKDSLHS RWLGSAPRRE AFDAEAYCLR FRITTVMLER
HKKGDVFPIA TLGSLDFQTV LYQWPAPLLM PSLFMSGDPN APFLASSLTI GGIDLADRLE
DLCDFLERRV SKTGTKSPKK DFSNIVDGFQ LPRSSIQVHC GVICVRLIQN GAQETSSSLE
MRTDGFTFEL NAKYDSDQTI ASTQTLPPNF SCFSGRLALS LHPVLLHVRS GWCSVGFASD
NEFLNDPAIL SMGPVEIGGS VRAEVEEELD IFRVKRASLS YDVHAIVDTF AIELWHADSV
SAAAELLAQL PTASVPASDG TLIAPSKPLS LPPGVVSIVL ARFIVVVTSP DINPKDVDLS
RGIGLKTMVS LELVNPAQSP RVQDEKLLKL RRSLGLTHKR LEDTIAASKG NVLHDNTSAL
LRLKIANLLL RKAFATQFET DDPFLAGRDD LTPTDQEFMR IPSVQLDVSI MGGDDRHTTR
QVTVTIPSIQ GKFELSNVYC SLLAAQTLQA LARTRQLVRP DAANSSSTSI KWSVDCRVQS
FNLQWALPNQ TLVSLLEDAR FSWLPNQSTR FEFKSLAFWV PTPILVHGWE YDHSQKWDQL
LTFYLWNISF PMVNHSLSID AVGQSLRLRI PHGYILADLI LDLIVVAKAT KHLVHIVKSG
VFSDIPSPEP EAPKISPNIS FEIQTLCVEA ADDPFEAKLS AIWRVGLDAV KQRLEREEAF
SAKVAAIQAG GDNSDTKVVA EGEHDYQFTA KHTVPLDDAR RRLDEVHFLD WKFRLQNLRE
AWSNHETSIL HKLYGPQGTT GRAPFPRSKV STNGMGIPPL FRVYISSLKL SVSLPTFPLE
ELPNFLHDQG GGLPIGTEFS LLVPLHIRFT LNTIRITARD FPIPLVHVQD SRDSILPACV
FDSDVVIAEE MGSDASSDWM DCPVLPANQG IYGTGALTLH VPKTIMPVKS YACPTIEIST
ACPTVLSWGV SYMSTLQDVV RVIESLSPNP RDPSPPIGFW DKLRLIAHWK VKFSFKEEVR
VYLKGSRDPV KIADDGAGFV LVWKGSPQLL IGYPNVQGDL LQLTSDTSLI AVPKFGEITS
DGTLNLTHLT MNSHRKICAE LHSGVRWGIG FVFERTCDAQ CGKCSGHVFQ RQCRLFDFVP
HYAVRLESKS SLPTLKGIDD SYKEFRSDFI HFSFSLTAST KEGCATTNAL HLTPKAFTHF
WAWWSLFDSV PTLRIRVGAY FTPRPVTPKF GRHIATIKYR IVLSKLFVMH GYLDDSPETW
ANGITSWIGV KGMVDEVRVD MHQRDQETQV RGIEPNTTKT AHRKPFYAAE TVLQGVDLRT
VFAIFADPLK AEISTNQHFS TPNTYLQYND LPQTSTTSSW YDTNDFIELD WESSSEPTLH
YLPLLSCPRF TYLKRNTAEA GGDQDSKFGI ENTHHCLLGQ ESSAPQIQIN LAAARIDELR
RYSTEDSAEV RIMMYALQNW LLTAFYHGAQ RTSGSRKRMI KLLQDYMDFL KNAETDDVLE
PLQAKSYHLP SEVVLPEEWT EFDNTYQLHC PKLSLEKATR DIMIQYYECS RARKGFEYHL
ATRAVKYIRD QAKASKVKAE PENKGGDSIS NKPAQLAASA IRKLLKGDVG KSSVEMDQQD
ALGLLCEPLD GWCAGVTLYK AHCCFLLKPQ VVLRDEDSGD ICVVAATQAK LQSFAIMDDA
NIDDPISGKI MSRNYTSLSG FQIFCPNHAA VSSTRLQVPL EVLIDRRCES DEFERLVPQT
DATFHYDKFN RLRLRNEVTS VVGPSLDTTP SISRTHLQDQ TDLIRMHIPH LTVSADDKHF
RTISNIVTKL LLFSDAAHKE RLDKLETLLF SYDFMDLRQA ADVITDLQSR LRAALETERV
LEHTPRHLPA EEFTKLGRLR LRSHILALTE ELDYLFGAIK LVQDRTDERM DQKSALLVHA
SSSEMSWKML GDDKDLLAKL VIEHSNFYWL SRQDSAMVND LVIGNLQAFD GSREAIWTEI
LLKDDEPANH PLHKRNLFLL AHWSILPPVG GISIYETFEV SLHPLKLQID AKLGRRIMEY
LWPDRRDRQR DSEDELASTW SHDTTHSEEF SVPKLPIRSS IDSPRGLQNL QSEDVSQNGR
LAPPSLRRLG SSRSFTDLRY TFGEYDRPQF LLSNGGSNGR PDSSDVHESF AAGAKFDATL
ELEEKTGDAA VMKTRSSQKT FIHVKVASMN LVLSILKEGS FECHDVRIKT RDLIYQNQTS
SFEELVNKFI PSNMSWKGWM KMVFHQPLIP VFPVARQILS KTKLVGSSRV IQSTEVDGSL
TSRRTEKKRT LTLRLPGKHW GRSIPTKLKK KPTHPTVVVP DVPIYTSQPL SAEPEPLKAN
EMEVIETSQE TNLETLKKPS SPS
//
