ID   K6H0H2_9GAMM            Unreviewed;       531 AA.
AC   K6H0H2;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN   ORFNames=B273_0493 {ECO:0000313|EMBL:EKO36043.1};
OS   SAR86 cluster bacterium SAR86E.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; SAR86 cluster.
OX   NCBI_TaxID=1208365 {ECO:0000313|EMBL:EKO36043.1, ECO:0000313|Proteomes:UP000010310};
RN   [1] {ECO:0000313|EMBL:EKO36043.1, ECO:0000313|Proteomes:UP000010310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SAR86E {ECO:0000313|EMBL:EKO36043.1};
RA   Dupont C.L., Rusch D.B., Lombardo M.-J., Novotny M., Yee-Greenbaum J.,
RA   Laskin R.;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC       mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC   -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC       localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC       {ECO:0000256|ARBA:ARBA00038825}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC       {ECO:0000256|ARBA:ARBA00004305}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKO36043.1}.
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DR   EMBL; AMWX01000012; EKO36043.1; -; Genomic_DNA.
DR   AlphaFoldDB; K6H0H2; -.
DR   STRING; 1208365.B273_0493; -.
DR   PATRIC; fig|1208365.4.peg.1088; -.
DR   Proteomes; UP000010310; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR   PANTHER; PTHR10668:SF103; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010310}.
FT   DOMAIN          19..330
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   531 AA;  57858 MW;  4E0F6799B8B9100B CRC64;
     MSYSQNSIDA IIIGAGHNGL VCAYYLAKKG LNVHVYEKRS IVGGAAVTEE FHPGFRNSVA
     SYTVSLLNPE IIKDMNLKEY GLEVVKRPIS NFLPIDQTTY LKLGGGLERT QEEFKKFSAK
     DAARLPEYYD RIEAVADVLR DLSIKTPPNP KQGIRAALNA ALQLWPIATK GNQVHRDVYD
     LFTKSARSFL DSWFENEHIK AAFGFDSIVG NYASPDTPGS AYVLLHHVFG EVDGEKGAWG
     HAIGGMGAIT QAMEKACKDN GVEIYTSASV SKVIIEDGAA TGIQLDDGSA IKAKKIISNL
     NPKLLYKKLI DESELDSEFN RSMDGYKCGS GTFRMNVALS ELPDFCALPG KEIAEHHQSG
     IVIAPTLDYM DKAYIDAKSH GWSSAPIVEM LIPSTMDNTL APEGQHVASL FCQQFSPHLA
     DGASWHDHRL AAADTIIETV TKHAPNFRES ILGMMILSPL DLEEKFGLIG GDIMHGQMSL
     DQMWAARPLM NYGNYRGPLK SLYMCGSGTH PGGGVTGLPG KNAAREILKD G
//