ID K6I6X1_9LEPT Unreviewed; 473 AA.
AC K6I6X1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=RNA polymerase sigma-54 factor {ECO:0000313|EMBL:EKO79340.1};
GN Name=rpoN {ECO:0000313|EMBL:EKO79340.1};
GN ORFNames=LEP1GSC068_0787 {ECO:0000313|EMBL:EKO79340.1};
OS Leptospira sp. Fiocruz LV3954.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1193012 {ECO:0000313|EMBL:EKO79340.1, ECO:0000313|Proteomes:UP000002809};
RN [1] {ECO:0000313|EMBL:EKO79340.1, ECO:0000313|Proteomes:UP000002809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fiocruz LV3954 {ECO:0000313|EMBL:EKO79340.1,
RC ECO:0000313|Proteomes:UP000002809};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Selengut J.D., Sanka R., DePew J.,
RA Ko A.I., Reis M.G., Ribeiro G.S., Wunder E.Jr., Vinetz J.M., Sutton G.G.,
RA Nelson W.C., Fouts D.E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKO79340.1}.
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DR EMBL; AKWV02000020; EKO79340.1; -; Genomic_DNA.
DR RefSeq; WP_004460646.1; NZ_AKWV02000020.1.
DR AlphaFoldDB; K6I6X1; -.
DR GeneID; 29741728; -.
DR PATRIC; fig|1193012.3.peg.1062; -.
DR Proteomes; UP000002809; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 112..295
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 308..466
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
SQ SEQUENCE 473 AA; 54882 MW; EF940B7BD5B1FA2C CRC64;
MNLSQSLVQK QTQKLVMTQD LRQSIELLPL STLELSDRIN SELVENPMLE EEYSSERNRT
PDLYSRDDLK RKEKNDFLKN SDVTWQDHFS LDKAGSAGSD ASDRNQKYIE SSPERSSLSE
HLLWQLRLSS LKPEEISIGE ILISMLDDHG FITVPIPDLC KEMKLNEKKV RKILDQIHRL
DPIGIGARDV QETLLIQARI VKPEDQKLHT MIRDHIKDLE KLDYKSISKK MEVSLETVES
LASEIKKLEP YPATLYTPNK PDYVIPDVIV REVEGEFDVY INDEWIPRLK INKEYKNILK
NAKESDREYI TSKLGSAEWL IRSVNQRRQT LFKVTSAIIE MQIEFFQKGI QYIKPLTLKD
IAEKLEMHES TISRITSNKY VQTSRGIMEL KWFFSSGVRS SEGGIESSKK IHDLIRNLVK
EEQFDHPLSD QEIVEAIGKQ GIEIARRTVA KYRKILKILP SSQRKKVKSL ESR
//
