ID K6PRH3_9FIRM Unreviewed; 1191 AA.
AC K6PRH3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=DNA/RNA helicase, superfamily II, SNF2 family {ECO:0000313|EMBL:EKP95522.1};
GN ORFNames=ThesuDRAFT_01274 {ECO:0000313|EMBL:EKP95522.1};
OS Thermaerobacter subterraneus DSM 13965.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Clostridiales Family XVII. Incertae Sedis; Thermaerobacter.
OX NCBI_TaxID=867903 {ECO:0000313|EMBL:EKP95522.1, ECO:0000313|Proteomes:UP000005710};
RN [1] {ECO:0000313|EMBL:EKP95522.1, ECO:0000313|Proteomes:UP000005710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13965 {ECO:0000313|EMBL:EKP95522.1,
RC ECO:0000313|Proteomes:UP000005710};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Detter J.C., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Pukall R.,
RA Wahrenburg C., Brambilla E., Klenk H.-P., Eisen J.A.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EKP95522.1, ECO:0000313|Proteomes:UP000005710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13965 {ECO:0000313|EMBL:EKP95522.1,
RC ECO:0000313|Proteomes:UP000005710};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Eisen J., Klenk H.-P.;
RT "Improved high-quality draft of Thermaerobacter subterraneus C21, DSM
RT 13965.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKP95522.1}.
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DR EMBL; AENY02000002; EKP95522.1; -; Genomic_DNA.
DR RefSeq; WP_006903542.1; NZ_JH976535.1.
DR AlphaFoldDB; K6PRH3; -.
DR STRING; 867903.ThesuDRAFT_01274; -.
DR eggNOG; COG0553; Bacteria.
DR eggNOG; COG4715; Bacteria.
DR HOGENOM; CLU_000315_21_0_9; -.
DR OrthoDB; 9814088at2; -.
DR Proteomes; UP000005710; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR013663; Helicase_SWF/SNF/SWI_bac.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR007527; Znf_SWIM.
DR PANTHER; PTHR10799:SF1020; BTAF (TBP-ASSOCIATED FACTOR) HOMOLOG; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF08455; SNF2_assoc; 1.
DR Pfam; PF04434; SWIM; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EKP95522.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00325};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00325}.
FT DOMAIN 61..98
FT /note="SWIM-type"
FT /evidence="ECO:0000259|PROSITE:PS50966"
FT DOMAIN 736..896
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1028..1180
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 104..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..196
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1191 AA; 131105 MW; 1B92B5FDE8F42563 CRC64;
MTRNPSFDEV LESLGEVLEA APERIFWRGR DYADDGRVLD LAWGPGPALR AQVEGTAREP
YRVAVWWDPT SDCWQATCSC PYEGWPCKHV VAAILRFMDR FEAGEDLPDD PGTTGPTAAA
AGDGTPPPAG ARPGEPAGGL ERAMAAGGPA RAVASSGPDR VPAPGGSDRA VPSGGSAPAP
ASSPPPGPPA SAPPAGSAPA GRPGSAGWRA EVDRWLERAG SDAPAGRGPQ SGRDGHPGAG
PQPGTDQVVV RLYFYPDGLR IAIHRARWGK QGLGKERPLH FDPLSPWLPS PAGPLHRLLF
RMLEHPVPHP GRPGAATYDP LYEIPPGMVD LCLELLGRLP FVFAGDGREP LRIEHEPYRV
EVVAVPAGDD LTLTTRWFTG DGRPWSPPAG SVGIPGERYL WVQWGPVLRP VLTAGDVALH
LAVGARPVTV PAAEVPDFIG RYLPRLQRRA RIQLPGALQQ QIRDGAPRPV ILLSEQEGAL
VVELAFAYGD GEPSIRAGDD EPALVPGGVR VWYRRRPDLE RAAWDQFAAA MAAVDAGPGP
DGSVRLFGDQ ALDFLAETLP RLAQRWEVRG QERLVRFRVS RSPLRSQVRV ATGIDWLDLD
VTLASPEGTA GWEALLDALQ RHSRYVRLDS GVMARLPEAW LQRLGVLAEH ARHHRRRRGA
GGEPRSSGEE PLRLSRWAFG VAAHLLEAAD RREADQGFRH LARLLDGFEG IPEMPLPRGL
KARLRPYQVR GYHWLCFVRD HGLHGILADD MGLGKTVQVL ALLLAEMEDG RAAAPSLVVV
PTSLVFNWVE EARRFAPDLR VLALTGPRRA PLFRQAGEYD LLITTYPLIW RDIAHLEARD
YHYLILDEAQ HVKNPDTQTW QALRRLRARH RLALTGTPVE NHVLDLWALF EILMPGYLGR
QEAFVRRYAG AAAEPAPADG RPDPRVAELR RRVFPFILRR VKDEVARDLP PRTEVVQYCE
MLPAQRKLYR ELLAAYRARV LAEVDRAGIA RSRMTILEAL LRLRQACCHP ALLDLPGYRN
AGSAKLEAFR DLVHHVAGGG GKVLVFSQFT SMLDILQREL DRLGLGWERL DGRVRNREER
VRRFQEGDVP VFLISLKAGG TGLNLTAASY VIHYDPWWNP AAEEQATGRA HRIGQDRPVF
SYKLITRGTV EEKILQLQEQ KRALAGALLA GDGQLGKDLT REDLEFLLAP D
//
