ID K6U6A2_9CLOT Unreviewed; 646 AA.
AC K6U6A2;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Hydrogenase, Fe-only {ECO:0000313|EMBL:EKQ56687.1};
GN ORFNames=A370_01762 {ECO:0000313|EMBL:EKQ56687.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ56687.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ56687.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ56687.1}.
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DR EMBL; ALXI01000064; EKQ56687.1; -; Genomic_DNA.
DR AlphaFoldDB; K6U6A2; -.
DR STRING; 1196322.A370_01762; -.
DR PATRIC; fig|1196322.3.peg.1706; -.
DR eggNOG; COG1143; Bacteria.
DR eggNOG; COG1894; Bacteria.
DR eggNOG; COG4624; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR PANTHER; PTHR11615:SF345; CATALYTIC SUBUNIT OF IRON-ONLY HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325}.
FT DOMAIN 214..242
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 243..272
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT COILED 182..209
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 646 AA; 72482 MW; 6537388DBD832D44 CRC64;
MGDNKTSFIQ SALGSVFSVF SPEELQELSN GRKIAICGKV NNPGIIEVPE GATLNDIIEQ
CGGLINKSNF KAAQIGLPFG GFLTQDSLDK EFDFGLFYDN IARTIIILSQ EDCIIQFEKF
YIEYLLAKIK DGSYKNYEIV KEDITEMFNI LNRISKGVSN MREIYILRNL AVTVKSKMKQ
KHNIMEEIIE KFYEEIEEHI EEKKCYTSQC NHLIKLTITK KCIGCGACKR ACPVDCIEGE
LKKKHNIDYN RCTHCGACVS ACPVDAITAG DNTLLFLRDL ATPNKIVITQ MAPAIRVAIG
EAFGFEPGDN VEKKLAAGLK KLGVNYVFDT TWGADLTIME EAAELQDRLE RHLAGDENVK
LPILTSCCPS WIKFIEQNYA DMLDVPSSAK SPMEMFAIVA KEIWAKEKGL SRDEVTSVAI
MPCIAKKYEA SRPEFSVDMN YDVDYVITTR ELIKIFENSG IDLKTLEDEE IDSVMGEYTG
AGIIFGRTGG VIEAAVRTAL ENITGNRIEN IEFEQLRGWD GFRICELEVD DIKLRIGVAH
GLREAAKMLD KIRSGEEFFH AIEIMACIGG CIGGGGQPKI KKNKQQVLEQ RAEGLNNIDR
SKVLRRSNEN PEVLAIYDKY LDHPLSNKAH ELLHTTYFPR MKKNND
//
