ID K6UBV2_9CLOT Unreviewed; 605 AA.
AC K6UBV2;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Retron-type reverse transcriptase {ECO:0000313|EMBL:EKQ57704.1};
GN ORFNames=A370_00693 {ECO:0000313|EMBL:EKQ57704.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ57704.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ57704.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ57704.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ALXI01000016; EKQ57704.1; -; Genomic_DNA.
DR AlphaFoldDB; K6UBV2; -.
DR STRING; 1196322.A370_00693; -.
DR PATRIC; fig|1196322.3.peg.675; -.
DR eggNOG; COG3344; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR CDD; cd01651; RT_G2_intron; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR025960; RVT_N.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF8; GROUP II INTRON-ASSOCIATED OPEN READING FRAME; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13655; RVT_N; 1.
DR SMART; SM00507; HNHc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:EKQ57704.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:EKQ57704.1};
KW Transferase {ECO:0000313|EMBL:EKQ57704.1}.
FT DOMAIN 100..337
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 605 AA; 71473 MW; B3182688E42A35C4 CRC64;
METYIKFNKS ATAPQVYDWN SINWRKIYKY VKKLRQRIFH AEQLGQKRKV RKLQRLMIRS
KANLLLSIKR VTQINKGKRT AGIDKMIIIN DNERIKLYNL IKNYNVKSIK VKPAKRTYIP
KKNGRLRPLG IPIIKDRIYQ NIVKNALEPQ WESRFESISY GFRPKRSAQD ARQQLFIKLR
AGTKRQWIFE GDFKGCFDNL NHEYIISCLD KFPCKETILE WLKAGYIDND VFNETIAGTP
QGGIISPLLA NIALHGMEEE LGVSYKHSTN GYYLEPNSIG IVKYADDFII LCKTEKDAKS
MYEKLKPYLE KRGLTLADDK TKVTHINEGF DFLSFNVKKY KTMRGTILLI KPSKASIKKA
KQKIKEVFDR YKGNPVGVII TKLNPIIRGI GNYWSSFVSK EAFKKIDYYI WIKVRKYLKF
MHPKKPWKWI IKKYFSNDIH GVSTAKWLLT DKSMKNCQLM KMQWIPIIRH QLIKYKNSPD
DGTLKEYFMK RDEKEFSRNN ILSRQKLAKK CRHQCRICNQ SLFSEENLKI NQIVPKVLGG
KDVYRNFEIL HESCHAQHQK LLKKYGGNKQ LSKIKKFFKD RQIEPSSKEG MKLMREQFKR
FEYNC
//
