ID   K7ACL1_9ALTE            Unreviewed;       836 AA.
AC   K7ACL1;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Peptidase S8/S53 subtilisin kexin sedolisin {ECO:0000313|EMBL:AGH43354.1};
GN   ORFNames=C427_1245 {ECO:0000313|EMBL:AGH43354.1};
OS   Paraglaciecola psychrophila 170.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Paraglaciecola.
OX   NCBI_TaxID=1129794 {ECO:0000313|EMBL:AGH43354.1, ECO:0000313|Proteomes:UP000011864};
RN   [1] {ECO:0000313|EMBL:AGH43354.1, ECO:0000313|Proteomes:UP000011864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=170 {ECO:0000313|EMBL:AGH43354.1,
RC   ECO:0000313|Proteomes:UP000011864};
RX   PubMed=23640379;
RA   Yin J., Chen J., Liu G., Yu Y., Song L., Wang X., Qu X.;
RT   "Complete Genome Sequence of Glaciecola psychrophila Strain 170T.";
RL   Genome Announc. 1:E00199-13(2013).
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR   EMBL; CP003837; AGH43354.1; -; Genomic_DNA.
DR   RefSeq; WP_007639399.1; NZ_BAES01000059.1.
DR   AlphaFoldDB; K7ACL1; -.
DR   STRING; 1129794.C427_1245; -.
DR   KEGG; gps:C427_1245; -.
DR   PATRIC; fig|1129794.4.peg.1237; -.
DR   eggNOG; COG1404; Bacteria.
DR   HOGENOM; CLU_344477_0_0_6; -.
DR   OrthoDB; 9790784at2; -.
DR   Proteomes; UP000011864; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR001119; SLH_dom.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   Pfam; PF00395; SLH; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51272; SLH; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000011864};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..836
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003902640"
FT   DOMAIN          607..670
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   ACT_SITE        150
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        202
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        403
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   836 AA;  88949 MW;  D4FC233173CFEC58 CRC64;
     MKKFTLSVLA AAVISVTLPS QVLAQAAIGE QLAQVLPTMS GEETIMAVVT FEQMSPVSVS
     QIRSLKALGI VKGVQFSAVP VMGLVANVAQ IEAIAARDDV RSVWLNRKLD YFNASSRQIT
     GVDKIQGAEF ANRNGGTEYT GKGVTIMVND SGIDATHQDL FFGDVVVDNV QAATHSLDLA
     ETGITDGFVI QGQPNTDLNV GHGTHCAGTI AGSGVMSDGK YKGVAPDADL VGYGSGAGLF
     ILDAVGGYDY AINHVYDYEH PLRVMSNSWG SGGKFDPKGP VNLASYKAYK FGILSVFAAG
     NAGSGENTHN PYAQIPWGMS VGAGDTNGNL VNFSSRGLEY ETGDFTMPDG TDWTYKNEVT
     IVAPGRYVIS TRSSTNMVAN GNQADSVIEP AYLPFYTRIS GTSMATPHAA GVVALVMEAN
     PSLNIDEVKQ LIKESATNMP GYEAWEVGAG YINARAAVAA AKGFDNNQKE TINNSSDSEF
     FANIDMQAQK ISEGKLAFDT VESQVIELEV GPNAKFVSVG VTALAAIKAI LEDPDGNRYE
     GDFTAPLLAD SSVITAPAKS GTWKLSMQPD AFGLEVSPLG VAYDEQAQTD EASDNRVTYW
     AWQDVYQGSD GMDDVIGHSQ QDAIENAVLE RLMDGRPTGQ FEPDSMLSRK ELAKALVMGA
     AVRQHRSLDN EPEIMITGVG NRYRTYAESV IVPGAALKDA KQQFGPVMMA DGGDFRGGDA
     VKRAELAYSL VQVIGKAQIA MDFGDDHQVT VNYNGQTITI ADQGTIPSDM RGYVQVALDE
     ELLGASYNIT QEQFGLEPKI GANFNPDNGI TRAGYAIIAN KIDSLYFVSG TASNAE
//