ID K7AQB5_PANTR Unreviewed; 1054 AA.
AC K7AQB5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=RNA binding motif protein 27 {ECO:0000313|EMBL:JAA20076.1};
GN Name=RBM27 {ECO:0000313|EMBL:JAA20076.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA20076.1};
RN [1] {ECO:0000313|EMBL:JAA20076.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skin {ECO:0000313|EMBL:JAA29853.1}, and Smooth vascular
RC {ECO:0000313|EMBL:JAA20076.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the turnover of nuclear polyadenylated
CC (pA+) RNA. {ECO:0000256|ARBA:ARBA00043866}.
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DR EMBL; GABF01002069; JAA20076.1; -; mRNA.
DR EMBL; GABD01003247; JAA29853.1; -; mRNA.
DR AlphaFoldDB; K7AQB5; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR CDD; cd12517; RRM_RBM27; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.20.1390.10; PWI domain; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045137; RBM26/27.
DR InterPro; IPR034451; RBM27_RRM.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14398; RNA RECOGNITION RRM/RNP DOMAIN; 1.
DR PANTHER; PTHR14398:SF1; RNA-BINDING PROTEIN 27; 1.
DR Pfam; PF01480; PWI; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 273..301
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 594..668
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT ZN_FING 273..301
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 91..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1008..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 806..880
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 166..181
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..354
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1046
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1054 AA; 118184 MW; BAABD70CD86AD8E6 CRC64;
MLIEDVDALK SWLAKLLEPI CDADPSALAN YVVALVKKDK PEKELKAFCA DQLDVFLQKE
TSGFVDKLFE SLYTKNYLPL LEPVKPEPKP LVQEKEEIKE EVFQEPAEEE RDGRKKKYPS
PQKTLSESSE RRTREKKRED GKWRDYDRYY ERNELYREKY DWRRGRSKSR SKSRGLSRSR
SRSRGRSKDR DPNRNVEHRE RSKFKSERND LESSYVPVSA PPPNSSEQYS SGAQSIPSTV
TVIAPAHHSE NTTESWSNYY NNHSSSNSFG RNLPPKRRCR DYDERGFCVL GDLCQFDHGN
DPLVVDEVAL PSMIPFPPPP PGLPPPPPPG MLMPPMPGPG PGPGPGPGPG PGHSMRLPVP
QGHGQPPPSV VLPIPRPPIT QSSLINSRDQ PGTSAVPNLA SVGTRLPPPL PQNLLYTVSE
RQPMYSREHG AAASERLQLG TPPPLLAARL VPPRNLMGSS IGYHTSVSSP TPLVPDTYEP
DGYNPEAPSI TSSGRSQYRQ FFSRTQTQRP NLIGLTSGDM DANPRAANIV IQTEPPVPVS
INSNITRVVL EPDSRKRAMS GLEGPLTKKP WLGKQGNNNQ NKPGFLRKNQ YTNTKLEVKK
IPQELNNITK LNEHFSKFGT IVNIQVAFKG DPEAALIQYL TNEEARKAIS STEAVLNNRF
IRVLWHRENN EQPTLQSSAQ LLLQQQQTLS HLSQQHHHLP QHLHQQQVLV AQSAPSTVHG
GIQKMMSKPQ TSGAYVLNKV PVKHRLGHAG GNQSDASHLL NQSGGAGEDC QIFSTPGHPK
MIYSSSNLKT PSKLCSGSKS HDVQEVLKKK QEAMKLQQDM RKKRQEVLEK QIECQKMLIS
KLEKNKNMKP EERANIMKTL KELGEKISQL KDELKTSSAV STPSKVKTKT EAQKELLDTE
LDLHKRLSSG EDTTELRKKL SQLQVEAARL GILPVGRGKT MSSQGRGRGR GRGGRGRGSL
NHMVVDHRPK ALTVGGFIEE EKEDLLQHFS TANQGPKFKD RRLQISWHKP KVPSISTETE
EEEVKEEETE TSDLFLPDDD DEDEDEYESR SWRR
//
