ID K7DIH0_PANTR Unreviewed; 738 AA.
AC K7DIH0;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Amyloid beta (A4) protein-binding, family B, member 2 {ECO:0000313|EMBL:JAA41549.1};
GN Name=APBB2 {ECO:0000313|EMBL:JAA41549.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA41549.1};
RN [1] {ECO:0000313|EMBL:JAA41549.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA41549.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GABE01003190; JAA41549.1; -; mRNA.
DR AlphaFoldDB; K7DIH0; -.
DR GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR CDD; cd01272; PTB1_Fe65; 1.
DR CDD; cd01271; PTB2_Fe65; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR039576; APBB1/2/3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR PANTHER; PTHR14058:SF11; AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2; 1.
DR Pfam; PF00640; PID; 2.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00462; PTB; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01179; PID; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 291..323
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 399..535
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 569..695
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 134..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 81089 MW; ABE99ED7BA397E18 CRC64;
MSEVLPADSG VDTLAVFMAS SGTTDVTNRN SPATPPNTLN LRSSHNELLN AEIKHTETKN
STPPKCRKKY ALTNIQAAMG LSDPAAQPLL GNGSANIKLV KNGENQLRKA AEQGQQDPNK
NLSPTTVINI TSEKLEGKEP HPQDSSSCEI LPSQPRRTKS FLNYYADLET SARELEQNRG
NHHGTAEEKS QPVQGQASTI IGNGDLLLQK PNRPQSSPED GQVATVSSSP ETKKDHPKTG
AKTDCALHRI QNLAPSDEES SWTTLSQDSA SPSSPDETAD IWSDHSFQTD PDLPPGWKRV
SDIAGTYYWH IPTGTTQWER PVSIPADLQG SRKGSLSSVT PSPTPENEDL HAATVNPDPS
LKEFEGATLR YASLKLRNAP HPDDDDSCSI NSDPEAKCFA VRSLGWVEMA EEDLAPGKSS
VAVNNCIRQL SYCKNDIRDT VGIWGEGKDM YLILENDMLS LVDPMDRSVL HSQPIVSIRV
WGVGRDNGRD FAYVARDKDT RILKCHVFRC DTPAKAIATS LHEICSKIMA ERKNAKALAC
SSLQERANVN LDVPLQVDFP TPKTELVQKF HVQYLGMLPV DKPVGMDILN SAIENLMTSS
NKEDWLSVNM NVADATVTVI SEKNEEEVLV ECRVRFLSFM GVGKDVHTFA FIMDTGNQRF
ECHVFWCEPN AGNVSEAVQA ACMLRYQKCL VARPPSQKVR PPPPPADSVT RRVTTNVKRG
VLSLIDTLKQ KRPVTEMP
//
