ID   K7EWK7_PELSI            Unreviewed;       477 AA.
AC   K7EWK7;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS   Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC   Trionychidae; Pelodiscus.
OX   NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000000167.1, ECO:0000313|Proteomes:UP000007267};
RN   [1] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG   Soft-shell Turtle Genome Consortium;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
RN   [3] {ECO:0000313|Ensembl:ENSPSIP00000000167.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AGCU01022398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; K7EWK7; -.
DR   Ensembl; ENSPSIT00000000167.1; ENSPSIP00000000167.1; ENSPSIG00000000168.1.
DR   eggNOG; KOG1075; Eukaryota.
DR   GeneTree; ENSGT00940000154136; -.
DR   HOGENOM; CLU_000680_20_5_1; -.
DR   OMA; CISNRAK; -.
DR   TreeFam; TF352460; -.
DR   Proteomes; UP000007267; Unassembled WGS sequence.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33332; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33332:SF52; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT   DOMAIN          23..278
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   477 AA;  54971 MW;  7989805E1D44FBCC CRC64;
     MHPRILKELI EEVSEPLAMI FEKSWQTGEI PEDWKRANIV PIYKKGNKNN PGNYRPVSLT
     SVPGKIMEQV IKEIICKHLE GNKVIGNSQH GFVKNKSCQT NLIAFFDKIT SLVDKGEAVD
     VIYLDFSKAF DTVSHDILID KLGKYNLDRA TIRWVHHWLD NRSQRVVVNG SKSCWKGITS
     GVPQGSVLGP VLFNIFINDV DIGIESTLIK FADDTKLGGV ATSVEDRDII QNDLSKLEKW
     SEVNRMRFNK EKCKVLHLGR NNQFHTYKMG SDCLGRSMAE RDLEVIVDHK LNMSQQCDAV
     AKKANMILGC INRCVVSKTR EVILPLYSAL VRPQLEYCVQ FWAPHFKKDV EKLERVQRRA
     TRMIKGLENM TYEARLHELG LFSLEKRRLR GDMIAVFQYL KGCHKEEGEN LFLLVSEDRT
     RSNGLKVQQG RFRLDIRKKF LTVRVVKYWN KLPREVVESP SLEIFKNRLD RHLSGMV
//