ID K7EWW3_PELSI Unreviewed; 782 AA.
AC K7EWW3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000000273.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000000273.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01116311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7EWW3; -.
DR Ensembl; ENSPSIT00000000273.1; ENSPSIP00000000273.1; ENSPSIG00000000273.1.
DR eggNOG; KOG1075; Eukaryota.
DR GeneTree; ENSGT00940000154136; -.
DR HOGENOM; CLU_000680_20_2_1; -.
DR OMA; NGATACE; -.
DR TreeFam; TF352460; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33395:SF21; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR33395; TRANSCRIPTASE, PUTATIVE-RELATED-RELATED; 1.
DR Pfam; PF00078; RVT_1; 1.
DR PRINTS; PR01345; CERVTRCPTASE.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 328..592
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 782 AA; 89507 MW; C659F854C818FEDB CRC64;
MGDFNHPDIC WETNTAVHRQ SRKFLENVGD NFLVQVLKDP TRGRAQLDLL LTNREELIGD
VEVGDNLGSS DHEMVDFRIL TKGRKESSKI HTLDFKKADF DSLRDLMERI PWDVNMKGKG
VQDSWQYFKE ALLKAQKETI PTRSKRGKPG RRPDWLTGEI LGVLKHKKEA YRKWKLGQMT
REELKCIVRE CRGVIRKAKA QMELRLAKDV KDNKKGFYRH VNKKVIREGV QSLMDEGGNL
VTEDVGKAEV LNAFFASVFT DKVGSWTSVL SDARWEEDGQ PLVGKEQVRN YLEKLNVHKS
MGPDLMHPRV LKELANVIEE PLAIIFEKSW RSDEIPDDWK KANVVPIFKK GKKDDPGNYR
PVSLTSVPGK IMEGIIKESI LRHLNERKVI RNSQHGFTKG KSCLTNLISF YDEVTGSVDM
GKSVDVIYLD FSKAFDTVSH NILASKLREC GLDKWTVRWI ERWLEGRAQR VVINGSMSGW
RSVSSGVPQG SVLGPVLFNI FINDLDEGID CTLSKFADDT KLGGEVDTLK GRDRVQSDLD
KLEDWATRNL MRFNKDKCRV LHLGRKNPKH SYRLGTNQLS SSSAEKDLGV TVDEKLDMSQ
QCALVAKKAN GILGCIKRSI ASRSRDVIIP LYSALVRPHL EYCVQFWAPH YKKDADALER
VQRRATKMIR GLEHMTYEER LRDLGLFSLQ KRRVRGDLIA AFNFLKGGSK EDGERLFSVV
TDGRTRSNGL KLWWERSRLD IRKNYFTRRV VKHWNGLPRE VVESPSLEVF KSRLDKALAG
LI
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