ID K7F793_PELSI Unreviewed; 515 AA.
AC K7F793;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Gigaxonin {ECO:0000313|Ensembl:ENSPSIP00000003903.1};
GN Name=GAN {ECO:0000313|Ensembl:ENSPSIP00000003903.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000003903.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000003903.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01084021; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006122732.1; XM_006122670.2.
DR AlphaFoldDB; K7F793; -.
DR STRING; 13735.ENSPSIP00000003903; -.
DR Ensembl; ENSPSIT00000003923.1; ENSPSIP00000003903.1; ENSPSIG00000003693.1.
DR GeneID; 102455727; -.
DR KEGG; pss:102455727; -.
DR CTD; 8139; -.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000155273; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR OMA; QHVHYVA; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF328485; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR CDD; cd18455; BACK_KLHL16_gigaxonin; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030579; KLHL16_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF232; GIGAXONIN; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 52..154
FT /note="BACK"
FT /evidence="ECO:0000259|SMART:SM00875"
SQ SEQUENCE 515 AA; 58577 MW; B8A783B9A43D37D0 CRC64;
MREILDYIFS GQIRLNEDTI QDVVQAADLL LLTDLKTLCC EFLESCIVAE NCIGIRDFAL
HYCLRHVHYL ASEYLETHFR DVSSTEEFLE LSPEKLKEVL SLEKLNVGNE RYVFEAVIRW
ISHDSELRKV HLKDVMSAVW VSGLDSIYLR EQMMSEPLVR EIVKECNNIP LTPPQQGEAM
LASFKPRGYS ECIVTVGGAE RASRKPTAVM RCMCPLYDPN RQLWIELAPM STPRINHGVL
SAEGFLFVLG GQDENKDTLS SGEKYDPDTN SWSSLPPMNE ARHNFGLVEI DGILYILGGE
DGERELSSME CYDIYNKTWT KQPDLTMVRK IGCYAAMKKK IYAMGGGSYG KLFESVECYD
PRTQQWTAIC PLKERRFGAV ACGVASELYV FGGVRSRDDN QATEMVTCKS EFYHDEFKRW
IYLNDQNLCI PASSSFVYGA VPIGASIYVI GDLDTGTNYD YVREFKRSTG TWHHTKPLFP
SDLRRTGCAA LRIANCKLFR LQLQQGLFRI RVPSP
//
