ID K7FI16_PELSI Unreviewed; 410 AA.
AC K7FI16;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Vacuolar protein 8 {ECO:0000256|ARBA:ARBA00026209};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000007676.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000007676.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004635}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004592}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004592}.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR EMBL; AGCU01092311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01092312; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FI16; -.
DR STRING; 13735.ENSPSIP00000007676; -.
DR Ensembl; ENSPSIT00000007717.1; ENSPSIP00000007676.1; ENSPSIG00000007058.1.
DR eggNOG; KOG4224; Eukaryota.
DR GeneTree; ENSGT00960000189180; -.
DR HOGENOM; CLU_558481_0_0_1; -.
DR OMA; VWDKPDG; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043495; F:protein-membrane adaptor activity; IEA:InterPro.
DR GO; GO:0071562; P:nucleus-vacuole junction assembly; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045156; Vac8.
DR PANTHER; PTHR47249; VACUOLAR PROTEIN 8; 1.
DR PANTHER; PTHR47249:SF1; VACUOLAR PROTEIN 8; 1.
DR Pfam; PF00514; Arm; 2.
DR SMART; SM00185; ARM; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT REPEAT 83..125
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 168..210
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 410 AA; 45345 MW; 1EFFFE635C26668A CRC64;
MGLLEPILEL LESCDSTVQC NSCACIMTLA VSESNQEAIS SAGVVPLLAL ANSYDPRIQQ
NAVGAILNLT RSERIQQILC KEGALPILIL LLECPDSEVQ YYSCTALSNV AANSQHHEAM
LRVGDRLLLR TLISLLSSSV DKVSCQACVC LRNLATNVNI QAEIIAMDIL PKLLTLLASN
NSDVQQASVA LLWILSQHPA NQDTLMQEEV LQNLGVLLLT CQKDPAIVGL SACIIKNLSL
FKNVQRIIES PCVGGLLQAI LSTETQEESL HYLTCSLAEL AKHEGATLHL LEWMNEPLIK
RLVRLAGQQE HTELSFQAAS IVRHMLCYDK VMSLLKCHLG EVQHYLMNFL NRQEIRFQQL
GISTLGKLQE DPEFSSAFSQ SQLMNHLEQI RHQTEETQEL LKMATSHKGS
//
