ID K7FWI2_PELSI Unreviewed; 302 AA.
AC K7FWI2;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Guanine nucleotide-binding protein G(o) subunit alpha {ECO:0000256|ARBA:ARBA00040796};
GN Name=GNAO1 {ECO:0000313|Ensembl:ENSPSIP00000012392.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000012392.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000012392.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01102413; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102416; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102417; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01102422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FWI2; -.
DR STRING; 13735.ENSPSIP00000012392; -.
DR Ensembl; ENSPSIT00000012452.1; ENSPSIP00000012392.1; ENSPSIG00000011162.1.
DR eggNOG; KOG0082; Eukaryota.
DR GeneTree; ENSGT00940000155883; -.
DR OMA; TDAKMVF; -.
DR TreeFam; TF300673; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001408; Gprotein_alpha_I.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF355; GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00441; GPROTEINAI.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023139};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 302 AA; 34717 MW; 223415EE4D7B5942 CRC64;
MKIIHEDGFS GEDVKQYKPV VYSNTIQSLA AIVRAMDTLG IEYGDKERRA DAKMVCDVVS
RMEDTEPFSP ELLSAMMRLW ADSGIQECFN RSREYQLNDS AQYYLDSLDR IGAPDYQPTE
QDILRTRVKT TGIVETHFTF KNLHFRLFDV GGQRSERKKW IHCFEDVTAI IFCVALSGYD
QVLHEDETTN RMHESLMLFD SICNNKFFID TSIILFLNKK DLFAEKIKKS PLTICFPEYT
GPNTYEDAAA YIQAQFESKN RSPNKEIYCH MTCATDTNNI QVVFDAVTDI IIANNLRGCG
LY
//
