ID K7G2X7_PELSI Unreviewed; 374 AA.
AC K7G2X7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Replication factor C subunit 2 {ECO:0000256|ARBA:ARBA00040745};
GN Name=RFC2 {ECO:0000313|Ensembl:ENSPSIP00000014638.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000014638.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000014638.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: The elongation of primed DNA templates by DNA polymerase
CC delta and epsilon requires the action of the accessory proteins
CC proliferating cell nuclear antigen (PCNA) and activator 1. This subunit
CC binds ATP. {ECO:0000256|ARBA:ARBA00037115}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000256|ARBA:ARBA00005378}.
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DR EMBL; AGCU01172275; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172279; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172281; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172282; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172283; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172284; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006136123.1; XM_006136061.2.
DR AlphaFoldDB; K7G2X7; -.
DR STRING; 13735.ENSPSIP00000014638; -.
DR Ensembl; ENSPSIT00000014706.1; ENSPSIP00000014638.1; ENSPSIG00000013050.1.
DR GeneID; 102444419; -.
DR KEGG; pss:102444419; -.
DR CTD; 5982; -.
DR eggNOG; KOG0991; Eukaryota.
DR GeneTree; ENSGT00550000075050; -.
DR OMA; SCNYSSQ; -.
DR OrthoDB; 275853at2759; -.
DR TreeFam; TF300585; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0031390; C:Ctf18 RFC-like complex; IEA:Ensembl.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:Ensembl.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0017116; F:single-stranded DNA helicase activity; IEA:Ensembl.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:Ensembl.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013748; Rep_factorC_C.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF5; REPLICATION FACTOR C SUBUNIT 2; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 88..214
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 374 AA; 41483 MW; 01740DF37E85F2B3 CRC64;
MPFCTAKPRS PFSPWGLVCA RQIGAVHWPP AQRGFSPEQH GVPRVLPGHC SCGVPRPGVE
KYRPVKLSEI VGNEDTVSRL EVFAREGNVP NIIIAGPPGT GKTTSILCLA RALLGPALKD
AVLELNASND RGIDVVRNKI KIFAQQKVTL PKGRHKIIIL DEADSMTDGA QQALRRTMEI
YSKTTRFALA CNASDKIIEP IQSRCAVLRY TKLTDAQILA RLMKIVEREN VQYTDDGLEA
IIFTAQGDMR QALNNLQSTY SGFGFINSEN VFKVCDEPHP LLVKEMIQHC VNANIDEAYK
ILAHLWRLGY SPEDIVGNIF RVCKTFQMPE YLKLEFIKEI GYTHMKIAEG VNSLLQMAGL
LARLCQKTAA PAES
//
