ID K7GCC8_PELSI Unreviewed; 365 AA.
AC K7GCC8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=1-acylglycerol-3-phosphate O-acyltransferase 5 {ECO:0000313|Ensembl:ENSPSIP00000017939.1};
GN Name=AGPAT5 {ECO:0000313|Ensembl:ENSPSIP00000017939.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000017939.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000017939.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000256|ARBA:ARBA00008655}.
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DR EMBL; AGCU01193772; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193773; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193775; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193776; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006137818.1; XM_006137756.1.
DR AlphaFoldDB; K7GCC8; -.
DR STRING; 13735.ENSPSIP00000017939; -.
DR Ensembl; ENSPSIT00000018022.1; ENSPSIP00000017939.1; ENSPSIG00000015856.1.
DR GeneID; 102457765; -.
DR KEGG; pss:102457765; -.
DR CTD; 55326; -.
DR eggNOG; KOG1505; Eukaryota.
DR GeneTree; ENSGT00950000182836; -.
DR HOGENOM; CLU_041844_2_0_1; -.
DR OMA; CPRIHIH; -.
DR OrthoDB; 2906776at2759; -.
DR TreeFam; TF314346; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:Ensembl.
DR GO; GO:0006639; P:acylglycerol metabolic process; IEA:Ensembl.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd07990; LPLAT_LCLAT1-like; 1.
DR InterPro; IPR032098; Acyltransf_C.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10983:SF76; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON; 1.
DR PANTHER; PTHR10983; 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED; 1.
DR Pfam; PF16076; Acyltransf_C; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 87..212
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 365 AA; 42606 MW; 8044A4B74B796F42 CRC64;
MLLSLVLHTY SMRYVLPAAV MLGTAPTYVL AWGAWRLLSA LLPARFYWEL DDRFYSIYQS
MVLFFFERYT GVQVIIYGDL PKNKENVVCL SNHQSTVDWI VADMLAIRQN ALGHIRYVLK
DGLKWLPLYG WYFSQHGGIY VKRSAKFNEE EMRNKLQAQV KTETPVYLVI FPEGTRYDPE
MRKVIADSQL FAEKEGLTVL KHVVTPRVKA THVAIDTMKN YLDAVYDVTI AYEGTMDHKG
QRKVAPSMTE FLCKECPKVH IYLDRIELKD IPEEQMYMRR WLHERFEIKD KLLMEFYDAK
DSKRRNKFPG KCVHSKLSLK KTLPSLLFLG GLTASMLLTE FGRKLYVNTW IYGTLIGYLW
VSIKA
//
