ID K7GD33_PELSI Unreviewed; 706 AA.
AC K7GD33;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=DNA polymerase iota {ECO:0000313|Ensembl:ENSPSIP00000018194.1};
GN Name=POLI {ECO:0000313|Ensembl:ENSPSIP00000018194.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000018194.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000018194.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGCU01177051; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01177052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7GD33; -.
DR STRING; 13735.ENSPSIP00000018194; -.
DR Ensembl; ENSPSIT00000018279.1; ENSPSIP00000018194.1; ENSPSIG00000016138.1.
DR eggNOG; KOG2095; Eukaryota.
DR GeneTree; ENSGT00940000159487; -.
DR HOGENOM; CLU_012348_9_0_1; -.
DR OMA; GNCDVMT; -.
DR TreeFam; TF324222; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0036464; C:cytoplasmic ribonucleoprotein granule; IEA:Ensembl.
DR GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1630; -; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR46404; DNA POLYMERASE IOTA; 1.
DR PANTHER; PTHR46404:SF1; DNA POLYMERASE IOTA; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR PIRSF; PIRSF036603; DPol_eta; 2.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 33..246
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 706 AA; 79156 MW; E98066EFA98047A9 CRC64;
PGIHAGPGRG SRAQCKHGPR GLRPTGSKAH RVIVHTDLDC FYAQVEMIHN PELRDKPLGV
QQKNLVVTCN YEARKLGIKK LMSIRDAKEK CPQMVLVNGE DLTQYREMSY KVTELLEEFS
PLVERLGFDE NFVDITELVE KRLVQLHRDG CSKVSVSGHV YNNQPVNLND VMHIRLLIGS
QIAAEMREVM YNRLGLTGCA GVASNKLLSK LVSGTFKPNQ QTVLLPESCQ DLLGSLDHIR
KVPGIGYKTT KRLELLGLSS VRDLQTFSPV ILEETLGVSV AQHIQKLSYG DDDSPVAPSG
PPQSLSDEDS FKKCSSEVEV EKKIEELLVN LLDRISKDGR KPHTIRLTIR KFSSAYKWFN
RESRQCPIPS QIIQKFGTGN DNVLTPLVGI LMKLFRKMIK VDEPFHLTLL SVCFLNLKSL
PSLTKGSIGF YLTQSSPPSS SGKKLREVTK DHKMEGDQVN SCNFVPDGRI RSIRTRESSL
ETNKCREETG INVCLLHLLP AGIDQEVFSQ LPEDIKGEIV SGKTGERIHI KNVLSQPLPF
SQEAQPFLAQ EKMYYSPNSR GADCTVSSSV SSEYFTSTSE LVKAIIHRPN ACCIFNLQDL
PEYSESAQMD NCMEKIRKEA LNFKSTDSIV LNLQRQQHFL QSHSSDSKEQ PIGTASQDKD
HREQASEEGR IVFPPNVDPS IFSELPTEMQ KELMAEWKNL KPLSKL
//
