ID K7GGZ9_PELSI Unreviewed; 276 AA.
AC K7GGZ9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=LDL receptor related protein 11 {ECO:0000313|Ensembl:ENSPSIP00000019560.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000019560.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000019560.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01032202; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01032203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7GGZ9; -.
DR Ensembl; ENSPSIT00000019651.1; ENSPSIP00000019560.1; ENSPSIG00000017362.1.
DR eggNOG; KOG4295; Eukaryota.
DR GeneTree; ENSGT00940000165711; -.
DR HOGENOM; CLU_042674_0_0_1; -.
DR OMA; CIDITMA; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR46876; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11; 1.
DR PANTHER; PTHR46876:SF1; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 227..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..170
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT REGION 181..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 12..24
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 19..37
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 31..46
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 276 AA; 29499 MW; C4CB6E0DE8F83120 CRC64;
MVHTALGCAG VCSRYQFICD DGCCIDITFA CDGVEQCPDG SDEAFCHNFS LGRKTVTHAA
ISTDQQRTIG LTKDADNSVE NTQKNTIRNQ PLLALDADKS NQSLSQGPKK QVNGFIPEQC
LVPPAVGPCK GHFPRWHFDV SSGTCLHFIY GGCQGNENNF LQESDCLSEC VGIHGAISQQ
TATDPSSQSN SDPGNISSGK KTKNENGIAV SKSDQAAAGH PVPETGAVLP LALGLAITAL
LLLMVACRLR LVRQKLKKAR PITSEESDYL INGMYL
//
