ID K7GIB5_PELSI Unreviewed; 1574 AA.
AC K7GIB5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Bromodomain adjacent to zinc finger domain 1A {ECO:0000313|Ensembl:ENSPSIP00000020026.1};
GN Name=BAZ1A {ECO:0000313|Ensembl:ENSPSIP00000020026.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000020026.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000020026.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGCU01049767; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01049768; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01049769; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01049770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 13735.ENSPSIP00000020026; -.
DR Ensembl; ENSPSIT00000020120.1; ENSPSIP00000020026.1; ENSPSIG00000017675.1.
DR eggNOG; KOG1245; Eukaryota.
DR GeneTree; ENSGT00940000158135; -.
DR HOGENOM; CLU_002479_1_0_1; -.
DR OMA; CEATGKD; -.
DR TreeFam; TF316326; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0016590; C:ACF complex; IEA:Ensembl.
DR GO; GO:0008623; C:CHRAC; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:Ensembl.
DR GO; GO:0006334; P:nucleosome assembly; IEA:Ensembl.
DR GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR CDD; cd05504; Bromo_Acf1_like; 1.
DR CDD; cd15627; PHD_BAZ1A; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037325; Acf1_Bromo.
DR InterPro; IPR047171; BAZ1A.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46510; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR PANTHER; PTHR46510:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 22..128
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 426..491
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 1161..1211
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 1466..1536
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 295..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 950..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1215..1451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..731
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..788
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1230..1269
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1292..1330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1343..1364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1433..1449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1574 AA; 180903 MW; 16A12EF553E3F020 CRC64;
MPLLHRKPFV REKPPADLRP DERVFYCRVT NEIFRDYDDF FERTILCNSL VWSCAVTGKP
GLTYQEALES EKRARLNLQS FPKALIVPVL YLATLTHRSR LHEICDEIFA YVKDRYFVGE
TVEVVRNNGA RLQCKILEVI APPHHNGMAN GHINSTEEDT IVISDSDDSE THNSSAQNGK
KKALIDPSLF KYKVQPIKKE LYESVTVKAS QIRHHSRRKH LFSRDRLKLF LKQHCEPHDG
VIRTKAMSVA KYKIAEQDFS YFFPDDPPTF IFSPANKRRG RPPKRVSISC EDKIANKQNT
PGNRSKVAQE RARFQKQKEE MQAMASEKAK LKREKAHAME AKKKEREDKE KKREELKKIV
EEERMKKKEE KERLKMEKEK EREKLREEKR KYLEYLKQWS KPREDMECDD LKELPVPIPV
KTRLPPEIFG DALMVLEFLH AFGELFDLQD EFPEGVTLEV LEEALAGNDT EGPLCELLFF
FLTAIFQAMA EEEEEVAKDQ IADAETKDLT EALDEDADPT KSALFAVATL AAAWPQLHQG
CNLKNLDLDS CTLSEILRLH ILASGADVTS ANAKYRYQKR GGFDATDDAC MELRLSNPGL
LKKLSSTSVY DLSPGEKMKI LHALCGKLLT LVSTRDFIED SVDILRQAKQ EFRELKAEQH
RKEREAAAAR IRKRKEDRLK EQEQKMKEKQ EKLKEEEQRN PAAEVSVGEE EREDLDTSTE
SKETERKEQD LDTVTEDEEE LGPNKKGRRG KKRGQNGFKD FTRQDETSCE KSEPLTAEEE
EALKREQQKK EKELLEKIQN ATACTNISPL GRDRMYRRYW IFPSVPGLFI EEDYSGLTED
MLLPRPCSFQ NSIQSHIINE LQVSTKTGES LKSSESTSNI DQDSCASVAV EVPRQVYKPN
RWCFYNSREQ LDQLLEALNS RGYRESALKE TLLQEKNRLY EQLNNFPVEK FHIPDKPQSD
NKPPSSGRGR IVNAHDTSQM SAEKQLELRL RDFLLDIEDR IYQGTLGAIK VTDRQSWRAA
LENGQYELLN EENKENGIIK AVNEDAEEME TDDQAKFIVK DRLVGLKTEA PSTASTNTST
PQPVNNVVRY LASALLQIEQ GTERRFLKAP LVQDANDGGR SYKTVLDRWR ESLLSSGSLS
QVFLHLSTLD RSIIWSKSIL NARCKMCRKK GDAESMVLCD GCDRGYHIYC IRPKLKAIPE
GDWFCPECRP KQRSRRLSSR QRPSMESDEE ASEQFEEEEE ETYYEEAGQS EEEDYEEEQE
EEDESQEEEE LSLSKQGRPQ VKLPLKMRAA KLNNPFSSQS SQRQTSGRYA SRSQHNTPKQ
NESSSKVTGR GIRKIKSAPP SVTKPSLRLN SRTTRQSQAS LQADVFVELL SPRRRRRGKN
TTDSTPENSP SLGFRIVATT DSRERVRRSP FSTQKFSLQD NESKRRGRKR QSTDSSPQTS
LNRRSSGRQG GVHELSAFEQ LVVELVRHDD SWPFMKLVSK IQVPDYYDII KKPIALNIIR
EKVNKCEYKL ASEFIEDIEL MFSNCFEYNP RNTSEAKAGI RLQAFFHVQA QKLGLPIASG
NVDHAAPAAK KSRI
//
