ID K7KIB7_SOYBN Unreviewed; 1674 AA.
AC K7KIB7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KRH61605.1, ECO:0000313|EnsemblPlants:KRH61605};
GN Name=100806831 {ECO:0000313|EnsemblPlants:KRH61605};
GN ORFNames=GLYMA_04G057400 {ECO:0000313|EMBL:KRH61605.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH61605.1};
RN [1] {ECO:0000313|EMBL:KRH61605.1, ECO:0000313|EnsemblPlants:KRH61605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH61605};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH61605.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH61605}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH61605};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH61605.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH61605.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC {ECO:0000256|ARBA:ARBA00035116, ECO:0000256|PROSITE-ProRule:PRU00657}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000837; KRH61605.1; -; Genomic_DNA.
DR RefSeq; XP_006578099.1; XM_006578036.2.
DR AlphaFoldDB; K7KIB7; -.
DR SMR; K7KIB7; -.
DR STRING; 3847.K7KIB7; -.
DR PaxDb; 3847-GLYMA04G06060-2; -.
DR EnsemblPlants; KRH61605; KRH61605; GLYMA_04G057400.
DR GeneID; 100806831; -.
DR Gramene; KRH61605; KRH61605; GLYMA_04G057400.
DR KEGG; gmx:100806831; -.
DR eggNOG; KOG0701; Eukaryota.
DR HOGENOM; CLU_000907_4_4_1; -.
DR InParanoid; K7KIB7; -.
DR OrthoDB; 342391at2759; -.
DR Proteomes; UP000008827; Chromosome 4.
DR ExpressionAtlas; K7KIB7; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0030422; P:siRNA processing; IBA:GO_Central.
DR CDD; cd18034; DEXHc_dicer; 1.
DR CDD; cd00593; RIBOc; 2.
DR CDD; cd18802; SF2_C_dicer; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.160.380; Dicer dimerisation domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 2.170.260.10; paz domain; 1.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR038248; Dicer_dimer_sf.
DR InterPro; IPR005034; Dicer_dimerisation_dom.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003100; PAZ_dom.
DR InterPro; IPR036085; PAZ_dom_sf.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR PANTHER; PTHR14950:SF46; ENDORIBONUCLEASE DICER HOMOLOG 3; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF03368; Dicer_dimer; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02170; PAZ; 1.
DR Pfam; PF00636; Ribonuclease_3; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00949; PAZ; 1.
DR SMART; SM00535; RIBOc; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF101690; PAZ domain; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 2.
DR PROSITE; PS51327; DICER_DSRBF; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50821; PAZ; 1.
DR PROSITE; PS00517; RNASE_3_1; 1.
DR PROSITE; PS50142; RNASE_3_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00657};
KW RNA-mediated gene silencing {ECO:0000256|ARBA:ARBA00023158}.
FT DOMAIN 73..248
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 414..575
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 601..691
FT /note="Dicer dsRNA-binding fold"
FT /evidence="ECO:0000259|PROSITE:PS51327"
FT DOMAIN 920..1034
FT /note="PAZ"
FT /evidence="ECO:0000259|PROSITE:PS50821"
FT DOMAIN 1059..1231
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 1272..1415
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 1486..1509
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 305..332
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 37..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1674 AA; 188021 MW; A7B44EF810347897 CRC64;
MNSNIDSTDH SQDQSRKRNL PDADDSPAPN FHIDSSDHNQ DQSKKRKQPN DEDSPSLESP
CSNMNPRRYQ IEVYEVARRR NTIAVLDTGS GKTLIAVMLM KEVGQAIKTS GVKKLIIFLA
PTVHLVNQQF KNIKFLTDFQ VEEYYGAKGV DTWTLKTWEK EISNNDVLVM TPQILLDALR
KAFLRMEMIC LIVIDECHRT IGNHPYTKIM KEFYHQANEK PKIFGMTASP VGKKGVSSTM
DCEDQISELE SILDSQRYTV EDRTEMDRCV PSAKESCRYY DQARFSALSL KPKIEALSFK
FDALLSENQS NYKDVENKFK TLSQRMSNEL AKILHCLEDL GILCAYEAVK ICHENFSKSE
GECEIYRKGY LQCITFLEEV IKLIEESLHL ADKKILEVDF NYSQAEDLGY ISPKLIELIK
LFQSFGESSQ VLCLIFVDRI ITAKVIQRFA KTVPNISHFT VSYLTGNNTS VDALAPKRQK
EILDSFRSGK VNLLFTTDVL EEGIHVPNCS CVIRFDLPKT VRSYVQSRGR SRQANSQFVV
MLERGNLKQR DQLFDIIRSE RSMTDASIYK EHESSLRACM VGKTNAYYVE STGASFTLDS
SVSLIHRYCG TLPRDKYSCV KPNFEFLSVE GGYQCKLILP SNSAFQTIIG PSGKDMRLAK
HLACFEACKK LHQMGALNEH LVPLIEDSSE DDHIVKNKES SSGAGTTKRK ELHGKANIHA
LSGAWGDKLT RVKFNAYKFE FTCNIVSEIY SGFALLIESE LDEDVGNVNL DLYLVSKIVK
ASVSSCGQVD LDAEQMMRAK CFHELFFNGL FGRLVLKSKS AGEREFLLQK DTNSLWSPKH
LYLLLPLEKL NDICEGSLQI NWCGINSCAS AIKFLRRKFS LVTGDCDDNG TITSPHDTSS
SEMECVGANK IHFANCVVDA DNIKDRVVLA IHTGKIYCII EIDSNLSAES PFYGNNEKSK
ESITFSDYFS KSYGISLRHP GQPMLRLKQS HNPHNLLFNF YEEDARDKSS KIGPAASKLP
VHVHIPPELL YILDVKRDVL KSLYLLPSLM YRIESLMLSS QLREEIDGQT SKFNIRSSLI
LESLTTLRCS ESFSMERLEL LGDSVLKYVV SCHLFLKYPK KHEGQLSARR SSAVCNSTLH
KLGTDRKLQG YIRDSAFEPR RWVAPGQRSI HLVCCDCGLE TLEVPLDAKF HTEDPKVVVG
KFCDRGHCWM CSKTIADCVE ALIGAYYVDG GLFASLNVMK WLGIGAELEL SLVDEAITAA
SLRTCLPKES EIASLEKKIG YEFSVKGLLL EAITHLSEKE LGIGCCYERL EFLGDSVLDL
LITWHLYQSH TDIDPGVLTD LRSASVNNDN FAQVAVRHNL HQHLLHSSGL LLSQISEYVK
VISESDPRSL PSISAPKALG DVVESIVGAI LIDTKLSLDQ VWNVFYSLLS PIVTPDKLEL
PPFRELNELC DSLGYFVKVK ENCEKVGSAM HVEVSVQLPN ALLVREGKGA NKKTAKGEAA
FYLLKDLEKQ GISHGSFMSK GKRDNPDHVY GSSHLKMDSS ILIEEHSSEP ASHKRHILDE
TNLTAINLSI NMKKGGPRTT LYEVCKKLQW PVPTFDSTEY KDRSLFESCE GLQGSKGQNC
FVSKITLCIP NYGNIESKGE ARSDKKTSFD SAAVQMLLEL QRLGKVEIDP LPSS
//
