ID K7LE88_SOYBN Unreviewed; 1390 AA.
AC K7LE88;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN Name=100792603 {ECO:0000313|EnsemblPlants:KRH38837};
GN ORFNames=GLYMA_09G161400 {ECO:0000313|EMBL:KRH38837.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EnsemblPlants:KRH38837};
RN [1] {ECO:0000313|EMBL:KRH38837.1, ECO:0000313|EnsemblPlants:KRH38837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH38837};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH38837.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH38837}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH38837};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH38837.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH38837.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM000842; KRH38837.1; -; Genomic_DNA.
DR RefSeq; XP_014617686.1; XM_014762200.1.
DR AlphaFoldDB; K7LE88; -.
DR SMR; K7LE88; -.
DR PaxDb; 3847-GLYMA09G29050-2; -.
DR EnsemblPlants; KRH38837; KRH38837; GLYMA_09G161400.
DR GeneID; 100792603; -.
DR Gramene; KRH38837; KRH38837; GLYMA_09G161400.
DR KEGG; gmx:100792603; -.
DR eggNOG; KOG1075; Eukaryota.
DR HOGENOM; CLU_001561_5_2_1; -.
DR InParanoid; K7LE88; -.
DR OrthoDB; 708156at2759; -.
DR Proteomes; UP000008827; Chromosome 9.
DR ExpressionAtlas; K7LE88; baseline and differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06222; RNase_H_like; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017:SF431; NB-ARC DOMAIN PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827}.
FT DOMAIN 10..178
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT COILED 117..144
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1390 AA; 159316 MW; 64359B08CC603475 CRC64;
MALQSRSSSL SYDVFLSFRG EDTRHGFTGH LYSALHSKGI HTFIDDEGLQ RGEEITPALV
KAIQESKIAI IVLSINYASS SFCLHELATI LECLMGKGRL VLPVFYKVDP SHVRHQNGSY
EEALAKHEER FKAEKEKLQK WKMALHQVAN LSGYHFKDGE GYEYKFIEKI VEQVSREINP
ACLHVADYPV GLEWQVRQVR KLLDIGSDDG VHMIGFHGMG GVGKSALARA VYNNLIIDEK
FDGFCFLENV REKSNKDGLE HLQRILLSKI LGEKDINLAS KQQGSSMIQS RLKEKKVVLI
LDDVDKHEQL QAMVGRPDWF GPGSKIIITT RDKQLLAPHQ VITTYEVKGL DEKDALQLLT
WKAFKKEKAD PNYVEVLQRA VTYASGLPLA LEVIGSNLFE KSIKEWESAL KKYKRIPKKE
ILEILKVSFD ALEEEEKSVF LDLACCLKGC KLTEAEDILH AFYDDCMKDH IGVLVEKSLV
VVKWNGIINM HDLIQDMGRR IDQQESPKEP GKRKRLWLSK DIIQVLEDNS GTSKIEIISL
DFSSSEKEAI VEWDGNAFKK MKNLKILIIR NVKFSKGPNY FPDSLIALEW HRYPSNCLPS
NFNSNKLVVC KLPDGCFTSI GFHGSQKKFR NIKVLKFDKC KFLSQIPDVS HLPSLEELSF
ERCDNLITVH DSIGFLNKLK ILSAKGCSKL RTFPPLNLTS LENLQLSYCY SLENFPEILG
EMENIRGLLL NHLLIKEFPV SIQNLIGLQY LHLSCRNFQL QSSIFTMFNL NIFSAKNCKG
WQWVNSEEGE ENMGSILSLK NGEFDVQYCD LYDDFFSTGF TQFAHVETLC LDGNNFTFLP
ECIKEFKLLR SLFVSNCKYL QEIRGVPPKL KSLHAINCIS LSSSSSSMFL NKELYEAEKI
SFCFTGATIP KWFNQQSRGP STSFWFRNEF PDRVLCLIIT PLDFWNLMGR ATPLVFINGK
LQELMIFQPI DTEYTMLELD HTYLFDLSKV CIIDDMFEVA LEKEWNHVEV TYVGLIETSL
VKATGIHIFM DEERRMDDIQ FDDPYRKRKL DHVLNSSESQ QLVKNHRLWS WVGPERIKIL
LRNIADGALS TNAERRYMHN SVNTSCLSCD ALEETCLHAL RDCPKVAAVW RSVLPLELEV
KFFNIDEVTL WLERNLSFSV DWATKFGFAV EVIWESRNEI DLLDPRASSP IYMIMMIIIR
YEDFIRAHPS HKLMMRDHIQ PCSSDHLFKW RPPVDPWLKL NVDGAIDPCS KTAACGGIFR
DYSGRFVLGF SVKLDMEYFC SFDEAEIWGV YHGIKIARQY DFGKIVVESD SAKAIRFVQD
GCPTYQQHSF PLCHELRALT LSATNYLDWS LIYREGNMAA ASFANFGLSM NQRAWIFSAC
PTFCAPFVDV
//
