ID K7N0U7_SOYBN Unreviewed; 1344 AA.
AC K7N0U7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN Name=100797269 {ECO:0000313|EnsemblPlants:KRG89379};
GN ORFNames=GLYMA_20G020200 {ECO:0000313|EMBL:KRG89379.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRG89379.1};
RN [1] {ECO:0000313|EMBL:KRG89379.1, ECO:0000313|EnsemblPlants:KRG89379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRG89379};
RC TISSUE=Callus {ECO:0000313|EMBL:KRG89379.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRG89379}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRG89379};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRG89379.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRG89379.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide;
CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16302;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
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DR EMBL; CM000853; KRG89379.1; -; Genomic_DNA.
DR RefSeq; XP_014628222.1; XM_014772736.1.
DR AlphaFoldDB; K7N0U7; -.
DR SMR; K7N0U7; -.
DR PaxDb; 3847-GLYMA20G02472-1; -.
DR EnsemblPlants; KRG89379; KRG89379; GLYMA_20G020200.
DR GeneID; 100797269; -.
DR Gramene; KRG89379; KRG89379; GLYMA_20G020200.
DR KEGG; gmx:100797269; -.
DR eggNOG; ENOG502SI7S; Eukaryota.
DR HOGENOM; CLU_001561_0_3_1; -.
DR InParanoid; K7N0U7; -.
DR OMA; HSRNEQQ; -.
DR OrthoDB; 1028382at2759; -.
DR Proteomes; UP000008827; Chromosome 20.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR045344; C-JID.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017:SF271; NBS-LRR DISEASE RESISTANCE PROTEIN; 1.
DR Pfam; PF20160; C-JID; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008827}.
FT DOMAIN 42..208
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1344 AA; 152680 MW; 9C3DA1F54D2F2AEF CRC64;
MLGGGSRSST RLIGQSSYSC PPRMVTISSE AASSFSFASP LKRYDVFISF RGEDTRNNFT
SHLYAAFQLN KIQAFIDNRL HKGDEISPSI FKAIKHCNLS VVVLSKHYAS STWCLRELAE
ILDHKKRGGH IVIPVFYKID PSHVRKQTGT YGKAFEKYER DVKHNMAMLQ KWKAALTEVA
NLVGWEFKNH RTENELIEGI VKDVMEKLNR IYPTEVKETL VGIDQNIAPI ESLLRIGSKE
VRIIGIWGMG GVGKTTIANA LFTKLSSQYE GSCFLANVRE EYENQGLGYL RNKLFSEVLE
DDVNLHISTP KVRSTFVMRR LRQKKVLIVL DDVDDSKKLE YLAAQHDCLG SGSIVIVTTR
DKHVISKGVD ETYEVKGLSL HHAVRLFSLN AFGKTYPEKG FEMLSKQVVD HANGNPLALK
VLGSLLHSRN EQQWANALRK LTKVPNAEIQ NVLRWSYDGL DYEQKNMFLD IACFFRGENI
ENVIRLLEIC GFYPYIGIKI LQEKSLVTFS DDGKVCMHDL IQEMGWEIVH RESIKDPGRR
SRLWDPKEVY DVLKNNRGTD AVEGIILDVS QISDLPLSYE TFSRMINIRF LKFYMGRGRT
CNLLLPSGLK SLPNKLMYLQ WDGYPSKSLP STFCTDNLVV LSMMESHVEK LWDGIKSFAS
LKEINLRASK KLTNLPDLSL APNLETIDVS HCTSLLHVPL SIQYVKKLLL FNLESCKNLK
SLPINIHLSS LEMFILRRCS SLDEFSVTSQ NMTNLDLRET AIKDFPEYLW EHLNKLVYLN
LESCSMLKSL TSKIHLKSLQ KLSLRDCSSL EEFSVTSENM GCLNLRGTSI KELPTSLWRN
NKLFTLVLHS CKKLVNFPDR PKLEDLPLIF NGVSSSESPN TDEPWTLSSL ADLSLKGSSI
ENLPVSIKDL PSLKKLTLTE CKKLRSLPSL PPSLEDLSLD ESDIECLSLS IKDLSHLKIL
TLTNYKKLMS PQDLPSSSKA SLLNESKVDS HLVSMKGLSH LQKFPLVKWK RFHSLPELPP
FLEELSLSES NIECIPKSIK NLSHLRKLAI KKCTGLRYLP ELPPYLKDLF VRGCDIESLP
ISIKDLVHLR KITLIECKKL QVLPELPPCL QSFCAADCRS LEIVRSSKTV LIEDRYAYYY
NCISLDQNSR NNIIADAPFE AAYTSLQQGT PLGPLISICL PGTEIPDWFS YQSTNSSLDM
EIPQQWFKDS KFLGFALCLV IGGFLQNSYE GYDPDVKCYH FVKSAFNSDP SVPFLGHCTT
VMQVPQGFNS DHMFICYYPT FNASILQDFK DLGMYYDANS LRLRVIFKFK GPYQRLDIVK
KCGVRPLLIA NTERFHIESE LQPE
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