ID K7QTA0_APICE Unreviewed; 286 AA.
AC K7QTA0;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Bone morphogenetic protein 5-like protein {ECO:0000313|EMBL:AFV74942.1};
DE Flags: Fragment;
OS Apis cerana (Indian honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=7461 {ECO:0000313|EMBL:AFV74942.1};
RN [1] {ECO:0000313|EMBL:AFV74942.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C10 {ECO:0000313|EMBL:AFV74942.1};
RX PubMed=23071321; DOI=10.1073/pnas.1208094109;
RA Kent C.F., Minaei S., Harpur B.A., Zayed A.;
RT "Recombination is associated with the evolution of genome structure and
RT worker behavior in honey bees.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:18012-18017(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; JX406711; AFV74942.1; -; Genomic_DNA.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF263; PROTEIN DECAPENTAPLEGIC; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 180..286
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFV74942.1"
FT NON_TER 286
FT /evidence="ECO:0000313|EMBL:AFV74942.1"
SQ SEQUENCE 286 AA; 32067 MW; 8C2182F5B7773BCD CRC64;
SWQAPRVHAK ASIQFDLSIP ASSPSVLHRF SNKTNRRATE KSHRRYRGVV SKYMLELYHR
RSDVDIVRAL EPIHVSGPIN DGAKILVFSV PPIDPDEVLE VAELLGVAGS ILRVRLDHMD
TFESCRSRRD DSWRAFNVTS AVATRGGGXV RFRVYGRVGY HPCGDGPILL LSYAKVRKKR
PRRSVQEEEA EEADEGPRRR RKNSCRRRSM YVDFALIAYD DWVVAPPGYE AYQCSGKCFY
PFGDHLSPTK HAIVQTLVHG ALQGVDQGGS KPVGRACCVP TRLAPT
//
