ID K7SV96_LOCMI Unreviewed; 781 AA.
AC K7SV96;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Toll-9 receptor {ECO:0000313|EMBL:AFV93995.1};
DE Flags: Fragment;
OS Locusta migratoria manilensis (Oriental migratory locust).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC Acridoidea; Acrididae; Oedipodinae; Locusta.
OX NCBI_TaxID=229990 {ECO:0000313|EMBL:AFV93995.1};
RN [1] {ECO:0000313|EMBL:AFV93995.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Midgut {ECO:0000313|EMBL:AFV93995.1};
RA Liu Y.;
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Toll-like receptor family.
CC {ECO:0000256|ARBA:ARBA00009634}.
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DR EMBL; JQ910652; AFV93995.1; -; mRNA.
DR AlphaFoldDB; K7SV96; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR017241; Toll-like_receptor.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24365:SF541; MSTPROX-RELATED; 1.
DR PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF13676; TIR_2; 1.
DR PIRSF; PIRSF037595; Toll-like_receptor; 3.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:AFV93995.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 212..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 626..768
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFV93995.1"
SQ SEQUENCE 781 AA; 89105 MW; 5C100C4AD2F4127E CRC64;
FLTTVPRYFG RSPKVLKITQ HRITKLSSKS FRGLERLEEL EISDGRLFEI SDDAFSSLRH
LRAVNLSHNE LSLVPRDAFA ACARLEQLDL SWNPLVLPSR GAALASPSLA ALDVSSCGLS
RLPERALALL PALSELRLRD NGLRQVSACA LPPDHRLVLL DVDPGVEWLA CAPQPEVSTA
AGRGRPAREQ PPPGDHWLGL AQLALVPSLE QWVFLTVAAL VVVLLLACIR RACKPEERPK
EHMYEILGGN QAAHLPVAPY TDLRISRIST STCETFGDSA RVSMADGESR QYLPNYFPTA
TCLTVLISTT LSSCVKAGGK YPDGDQASTH KFQNLHVPLE LSDANVADNL TTNRHNSSYI
GSQSHIIFTK VIHITRFKGL PCHFQTSDFP TVKRQTFFNL QPTGRYTFSQ EPCISFGCKL
RKVFSFIVRK SDHLKMTAEP VETSHVNYHI IKLNCLFSFN YIISIFYFNI CTVADGMLYQ
ETSPCMEKCR KESKYNENLQ QMIDYLNSSR KAEDINLEII GWNEGAYRCL DNSGRRNIEN
FKFEDWQCFP NDKMGYTTPE EQITATWKIV VIVVSCVIVL MLGICYWKWR YIYQFGRAVR
SATMLRLLDD EKDKPNKAES NGHSNFSYDV FISYSDPNRQ WVLEELVPNF ENGSDLKVCL
HERDFQVGLS ILENIISCMD QSRILLLVIS QAFLRSQWCQ FELHMAQHRL LETRREDLIL
VLLEEIPTSR RPKMLRYLML TKTYIQWPGY DAGAEELKMF WKRLRRAVLL PRMMQNQDTF
A
//
