ID K7TQH6_MAIZE Unreviewed; 367 AA.
AC K7TQH6;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Splicing factor U2af large subunit {ECO:0000256|RuleBase:RU364135};
DE AltName: Full=U2 auxiliary factor 65 kDa subunit {ECO:0000256|RuleBase:RU364135};
DE AltName: Full=U2 small nuclear ribonucleoprotein auxiliary factor large subunit (U2 snRNP auxiliary factor large subunit) {ECO:0000256|RuleBase:RU364135};
GN ORFNames=ZEAMMB73_Zm00001d048655 {ECO:0000313|EMBL:AQK48338.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQK48338.1};
RN [1] {ECO:0000313|EMBL:AQK48338.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK48338.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for the splicing of pre-mRNA.
CC {ECO:0000256|RuleBase:RU364135}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364135}.
CC -!- SIMILARITY: Belongs to the splicing factor SR family.
CC {ECO:0000256|ARBA:ARBA00010269, ECO:0000256|RuleBase:RU364135}.
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DR EMBL; CM000780; AQK48336.1; -; Genomic_DNA.
DR EMBL; CM000780; AQK48338.1; -; Genomic_DNA.
DR EMBL; CM000780; AQK48342.1; -; Genomic_DNA.
DR EMBL; CM000780; AQK48343.1; -; Genomic_DNA.
DR EMBL; CM000780; AQK48344.1; -; Genomic_DNA.
DR AlphaFoldDB; K7TQH6; -.
DR HOGENOM; CLU_021795_1_1_1; -.
DR ExpressionAtlas; K7TQH6; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd12230; RRM1_U2AF65; 1.
DR CDD; cd12231; RRM2_U2AF65; 1.
DR CDD; cd12232; RRM3_U2AF65; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR006529; U2AF_lg.
DR NCBIfam; TIGR01642; U2AF_lg; 1.
DR PANTHER; PTHR23139; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR23139:SF114; SPLICING FACTOR U2AF LARGE SUBUNIT B; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 3.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|RuleBase:RU364135};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|RuleBase:RU364135};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364135};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 33..116
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 153..231
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 367 AA; 39493 MW; 205739F275DD38D4 CRC64;
MFPNMLPFGV AGQFNPLVIQ PQAMTQQATR HARRVYVGGL PPSANEQTVA IYFNQVMAAI
GGNTAGPGDA VLNVYINHDK KFAFVEMRSV EEASNAMALD GIMFEGAPVK VRRPTDYNPS
LAAALGPSQP SPNLNLAAVG LTAGSNGGLE GPDRIFVGGL PYYFTEAQVR ELLESFGPLR
GFDLVKDRET GNSKGYAFCV YQDLTVTDIA CAALNGIKMG DKTLTVRRAN QGASQPRPEQ
ESILLQAQQQ VQLQKLVYQV GALPTKVVCL TQVVTADELK DDEEYEDIME DMRLEAGKYG
NLVKVIIPRP DPSGQPVVGV GKVFLEYADI DGAAKAKTAL HGRKFGGNPV VAVCYAEDKF
ANGEYDG
//
