ID K7V4Q1_MAIZE Unreviewed; 887 AA.
AC K7V4Q1;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Putative phospholipase, patatin family protein {ECO:0000313|EMBL:AQL00295.1};
GN Name=103636624 {ECO:0000313|EnsemblPlants:Zm00001eb370460_P002};
GN ORFNames=ZEAMMB73_Zm00001d012687 {ECO:0000313|EMBL:AQL00295.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AQL00295.1};
RN [1] {ECO:0000313|EnsemblPlants:Zm00001eb370460_P002, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb370460_P002,
RC ECO:0000313|Proteomes:UP000007305};
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [2] {ECO:0000313|EMBL:AQL00295.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQL00295.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:Zm00001eb370460_P002}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb370460_P002};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- FUNCTION: Possesses non-specific lipolytic acyl hydrolase (LAH)
CC activity. Hydrolyzes phospholipids as well as galactolipids. May play a
CC role in disease resistance. {ECO:0000256|ARBA:ARBA00025642}.
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DR EMBL; CM000784; AQL00295.1; -; Genomic_DNA.
DR RefSeq; XP_008657202.1; XM_008658980.1.
DR AlphaFoldDB; K7V4Q1; -.
DR IntAct; K7V4Q1; 4.
DR STRING; 4577.K7V4Q1; -.
DR PaxDb; 4577-GRMZM2G035421_P01; -.
DR EnsemblPlants; Zm00001eb370460_T002; Zm00001eb370460_P002; Zm00001eb370460.
DR GeneID; 103636624; -.
DR Gramene; Zm00001eb370460_T002; Zm00001eb370460_P002; Zm00001eb370460.
DR KEGG; zma:103636624; -.
DR eggNOG; KOG2214; Eukaryota.
DR HOGENOM; CLU_013822_0_0_1; -.
DR InParanoid; K7V4Q1; -.
DR OMA; NHHVQQN; -.
DR OrthoDB; 154387at2759; -.
DR Proteomes; UP000007305; Chromosome 8.
DR ExpressionAtlas; K7V4Q1; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07231; Pat_SDP1-like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR021771; Triacylglycerol_lipase_N.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR Pfam; PF11815; DUF3336; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 1: Evidence at protein level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:K7V4Q1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..435
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 820..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 98209 MW; 2F70843FC27F30DB CRC64;
MDDIASEAPV GAFAIGPSTA LGGAVALRVL LCGSAARLRH RLAAALRAAL PVAAAWLHPR
DNTRGILLAV CAVALLLRGR RGRAGLRARV QSAYRCKFWR NMMRAALTYE EWAHAARMLE
LEAAPRRASD ADLYDEELVR NKLRELRHRR QEGSLRDIVF CMRADLLRNL GNMCNPELHK
GRLQVPRLIK EYIEEVSTQL KMVCDSDSDE LPLEEKLAFM HETRHAFGRT ALLLSGGASL
GSFHVGVVKT LVEHKLLPRI VSGSSVGSIM CSIVATRSWP ELESFFEEWH SLKFFDQMGG
IFPVVKRILT HGALHDIRHL QVLLRNLTSN LTFQEAYDIT GRILVVTVCS PRKHEPPRCL
NYLTSPHVLI WSAVTASCAF PGLFEAQELM AKDRFGQTIP FHAPFLLGME ERTVAPTRRW
RDGSLESDLP MKQLKELFNV NHFIVSQANP HIAPLLRLKE IIRAYGGSFA AKLAELAEME
VKHRCNQVLE LGFPLGGLAK LFAQDWEGDV TVVMPATLAQ YSKMIQNPSY AELQKAANQG
RRCTWEKLSA IRANCAIELA LDECVALLNH LRRLKRSAER ASASQGYGPV IRFCPSRRIP
SWNLIARENS TGSLDEEMLA SPHTNHQGPG GVAGTSTRNQ YLQRNAHESS DSESESIDLH
SWTRNGGPLM RTASANKFIS FVQNLEIDTE FRTIPSRENL TDLVTPNAGT LAAHAVSREA
TDRSLDISAL DIHDTATPRS TFGRSTSIVV SEGDLLQPEK IENGILFNVV RRDTLLESSS
GVESQGSPRE PDVETVQTEC LDGISASDDD DKELNVIVDE ATDPMSSNNL QDQGSSLEEN
SYSHFPLNSA DETSTNKPET ASIFDICTEM HPASISLPQG SSEKAEL
//
