ID   K7X4V0_DROSI            Unreviewed;       222 AA.
AC   K7X4V0;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Mitochondrial cardiolipin hydrolase {ECO:0000256|ARBA:ARBA00040549};
DE   AltName: Full=Mitochondrial phospholipase {ECO:0000256|ARBA:ARBA00043167};
DE   Flags: Fragment;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240 {ECO:0000313|EMBL:AFX62710.1};
RN   [1] {ECO:0000313|EMBL:AFX62710.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24361206; DOI=10.1016/j.gene.2013.11.095;
RA   Fablet M., Akkouche A., Braman V., Vieira C.;
RT   "Variable expression levels detected in the Drosophila effectors of piRNA
RT   biogenesis.";
RL   Gene 537:149-153(2014).
CC   -!- SIMILARITY: Belongs to the phospholipase D family. MitoPLD/Zucchini
CC       subfamily. {ECO:0000256|ARBA:ARBA00038012}.
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DR   EMBL; JX656770; AFX62710.1; -; mRNA.
DR   AlphaFoldDB; K7X4V0; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR   InterPro; IPR025202; PLD-like_dom.
DR   PANTHER; PTHR43856; CARDIOLIPIN HYDROLASE; 1.
DR   PANTHER; PTHR43856:SF1; MITOCHONDRIAL CARDIOLIPIN HYDROLASE; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
PE   2: Evidence at transcript level;
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022963}.
FT   DOMAIN          66..208
FT                   /note="Phospholipase D-like"
FT                   /evidence="ECO:0000259|Pfam:PF13091"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AFX62710.1"
SQ   SEQUENCE   222 AA;  24954 MW;  65BBEF53818B30C7 CRC64;
     VIWKLVQCSR SKREKASRVH EVIVFNELGE ICAAAHMRNN GIGSQKPQMS PCCNAHCSLR
     NVAKIAEQID RAVYSIDLAI FIFSSLSLAD ALKRALQRGV IIRIISDGEM VYCTGSQITM
     LAQLGVPVRV PITTNLMHNK FCIIDGMERV EEIRLLRKPK WMRPCYGIVI SGSLNWTAQG
     LGGNWENCII TADEKLTATF QAEFQRMWRA FGKTEASRIQ PK
//