ID K7YCR9_HELPX Unreviewed; 858 AA.
AC K7YCR9;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=VirB4 type IV secretion ATPase {ECO:0000313|EMBL:AFX90873.1};
GN ORFNames=HPAKL117_02290 {ECO:0000313|EMBL:AFX90873.1};
OS Helicobacter pylori Aklavik117.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1055531 {ECO:0000313|EMBL:AFX90873.1, ECO:0000313|Proteomes:UP000010079};
RN [1] {ECO:0000313|EMBL:AFX90873.1, ECO:0000313|Proteomes:UP000010079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aklavik117 {ECO:0000313|EMBL:AFX90873.1};
RX PubMed=25883278;
RA Kersulyte D., Bertoli M.T., Tamma S., Keelan M., Munday R., Geary J.,
RA Veldhuyzen van Zanten S., Goodman K.J., Berg D.E.;
RT "Complete Genome Sequences of Two Helicobacter pylori Strains from a
RT Canadian Arctic Aboriginal Community.";
RL Genome Announc. 3:0-0(2015).
CC -!- SIMILARITY: Belongs to the TrbE/VirB4 family.
CC {ECO:0000256|ARBA:ARBA00006512}.
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DR EMBL; CP003483; AFX90873.1; -; Genomic_DNA.
DR RefSeq; WP_015085629.1; NC_019560.1.
DR AlphaFoldDB; K7YCR9; -.
DR KEGG; hpya:HPAKL117_02290; -.
DR PATRIC; fig|1055531.3.peg.469; -.
DR HOGENOM; CLU_023569_0_0_7; -.
DR Proteomes; UP000010079; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004346; CagE_TrbE_VirB.
DR InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019476; T4SS_TraD_DNA-bd.
DR NCBIfam; TIGR00929; VirB4_CagE; 1.
DR Pfam; PF03135; CagE_TrbE_VirB; 1.
DR Pfam; PF10412; TrwB_AAD_bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 214..412
FT /note="CagE TrbE VirB component of type IV transporter
FT system central"
FT /evidence="ECO:0000259|Pfam:PF03135"
FT DOMAIN 471..541
FT /note="Type IV secretion system coupling protein TraD DNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF10412"
FT REGION 155..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 98885 MW; 7230E84AB023A1BE CRC64;
MFENALKYCK EKAIDLLTGF VPKTYSMTEE CNILGLYDDT FIITKQENLV AIMSLQGLSY
SNLMQKDLEG YFDTRQNVLN TISKDIQLRI VAKRRKEFIN QSPNIDNPYA KAIITQFESK
EIYKTEYFLV FESITSNVKS FFEKKKLEMT TSINEELEES SKENKQENEN SSNETHSNTS
SKKDKKNKFK KKTTFSATSK RALLIQTIER VKNALREFKP TLLNSKEVLN FYAEYINGKY
IAFNPKLKRL SDSYIASNIH FKKDYFIIEF QNQSTFCACV GIKNYESEEI SSLPISTLLH
TQIELDLIFH IRSLGQFESL NFLKTKKKLT LSKIVKNDID DYIELVQANR LSMQECALNL
VLRAKSKAKL DKSLKEILSL LNNAGLGSVT ETIGLKPSYF SFFPNNANIN PRMRNQTSQV
IASLILFEKN NTGFRANSWG DMPLSVFKNL DHSPYLFNFH NQEVKHKGVL AHNVARVVGH
TMIIGATGAG KTTLISYLMM SALKYPNIDI LALDRLNGLY SFTKYFDGFY NEGKDFHINP
FSLEDSPSNR AFLLHFYAQM AKVDSYDKHN DKIEDRTALL NAIDTMYRNY NDEVKQAKFS
NQELPLPFDL KEFVNSIVKT NTNILDSSFE EYLKSSLFSS RMDSLDFKTR ISTINTDSIL
HNDDDAGLLV YYVFHKMIDR ALRINRGFLC FIDEFKSYAQ NEMMNKKINE IITQARKANG
VIVLALQDIN QLSEVRNAQS FIKNMGQLIL YPQRNIDTKD LNDKFGIRLS DTEKHFLENT
AVNEYKVLLK NMNDGSSNII DVSLSSLGNY LQIFSSNSSM VEHIENLIKH YPTTWKEVFV
NNTYQKFDDK KHLEKVLA
//
