ID K8E742_9FIRM Unreviewed; 422 AA.
AC K8E742;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Glycerol-3-phosphate transporter {ECO:0000313|EMBL:CCO07298.1};
GN Name=glpT {ECO:0000313|EMBL:CCO07298.1};
GN ORFNames=DESHY_110242 {ECO:0000313|EMBL:CCO07298.1};
OS Desulforamulus hydrothermalis Lam5 = DSM 18033.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121428 {ECO:0000313|EMBL:CCO07298.1, ECO:0000313|Proteomes:UP000009315};
RN [1] {ECO:0000313|EMBL:CCO07298.1, ECO:0000313|Proteomes:UP000009315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lam5 / DSM 18033 {ECO:0000313|Proteomes:UP000009315};
RX PubMed=23405336; DOI=10.1128/genomeA.00114-12;
RA Amin O., Fardeau M.L., Valette O., Hirschler-Rea A., Barbe V., Medigue C.,
RA Vacherie B., Ollivier B., Bertin P.N., Dolla A.;
RT "Genome Sequence of the Sulfate-Reducing Bacterium Desulfotomaculum
RT hydrothermale Lam5(T).";
RL Genome Announc. 1:e00114-e00112(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO07298.1}.
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DR EMBL; CAOS01000003; CCO07298.1; -; Genomic_DNA.
DR RefSeq; WP_008410120.1; NZ_CAOS01000003.1.
DR AlphaFoldDB; K8E742; -.
DR STRING; 1121428.DESHY_110242; -.
DR eggNOG; COG2271; Bacteria.
DR Proteomes; UP000009315; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015169; F:glycerol-3-phosphate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17345; MFS_GlpT; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR005267; G3P_transporter.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR021159; Sugar-P_transporter_CS.
DR InterPro; IPR000849; Sugar_P_transporter.
DR NCBIfam; TIGR00881; 2A0104; 1.
DR NCBIfam; TIGR00712; glpT; 1.
DR PANTHER; PTHR43826; GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4; 1.
DR PANTHER; PTHR43826:SF6; GLYCEROL-3-PHOSPHATE TRANSPORTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PIRSF; PIRSF002808; Hexose_phosphate_transp; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS00942; GLPT; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009315};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 5..20
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..415
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 422 AA; 46320 MW; 0A2C5EA816ACBBFB CRC64;
MRRQVFIGIF VGYAGYYLVR KNFSLAVPYL VQEGFTKAEL GWVMSALAIS YGLSKFVMGV
FSDRSNPRYF MAAGLMFSAL ISIMYGAVPW ATSTVAVMYA LMFANGWVQG MGWPPCGRTM
THWYSVSERG TKVAVWNVAH NVGGGIIGPL ASLGILLFVD WHSVFYFPAI IALAVAVFII
LTVRDTPQSC GLPPIEEYKN EYPAEHAGSD LERELSAKEI LFKYVLNNKF LWYIALANVF
VYLVRYGVLD WAPTYLTEVK DFSHNSSRWA YFLYEYAGIP GTILCGWLSD KVFRGRRAPA
GIVFMIGVAV AVLVYWFNPP GNPLVDNLAL IAIGFLIYGP VMLIGLHALD LVPKKAAGTA
AGFTGLFGYM GGTVMANAAI GKTVDVFGWD GGFVMLVGAC VLAIFFMALT WNHGAKVKTN
NG
//
