ID   K8GPG3_9CYAN            Unreviewed;       732 AA.
AC   K8GPG3;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Putative polyglutamate capsule biosynthesis protein {ECO:0000313|EMBL:EKQ69589.1};
GN   ORFNames=OsccyDRAFT_2225 {ECO:0000313|EMBL:EKQ69589.1};
OS   Leptolyngbyaceae cyanobacterium JSC-12.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae.
OX   NCBI_TaxID=864702 {ECO:0000313|EMBL:EKQ69589.1, ECO:0000313|Proteomes:UP000001332};
RN   [1] {ECO:0000313|EMBL:EKQ69589.1, ECO:0000313|Proteomes:UP000001332}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSC-12 {ECO:0000313|EMBL:EKQ69589.1,
RC   ECO:0000313|Proteomes:UP000001332};
RG   DOE Joint Genome Institute;
RA   Brown I., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA   Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA   Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA   Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RT   "Improved high quality draft of Oscillatoriales sp. JSC-12.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CapA family.
CC       {ECO:0000256|ARBA:ARBA00005662}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKQ69589.1}.
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DR   EMBL; AJUB01000010; EKQ69589.1; -; Genomic_DNA.
DR   AlphaFoldDB; K8GPG3; -.
DR   STRING; 864702.OsccyDRAFT_2225; -.
DR   PATRIC; fig|864702.5.peg.2391; -.
DR   eggNOG; COG2843; Bacteria.
DR   HOGENOM; CLU_027136_0_0_3; -.
DR   OrthoDB; 9810906at2; -.
DR   Proteomes; UP000001332; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07381; MPP_CapA; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR019079; Capsule_synth_CapA.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   PANTHER; PTHR33393:SF11; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   Pfam; PF09587; PGA_cap; 1.
DR   SMART; SM00854; PGA_cap; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001332};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        146..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          219..452
FT                   /note="Capsule synthesis protein CapA"
FT                   /evidence="ECO:0000259|SMART:SM00854"
FT   REGION          172..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          512..732
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        512..528
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        529..556
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        637..719
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   732 AA;  79933 MW;  B60AAE4CF8E984A2 CRC64;
     MVQSSGLYYT SVYESAQRGN VRAIAAWLNQ VLLPYGIRAR LGAKHPGALK VLVEFDFPYD
     RSNPPRVWRE QLIRLICHRL WKLNSPVIHG VSVTARFVDQ PKRLVWRQSV RIVTPANKLR
     RQQSSQLRSR IRQTSRRKNR LRLARTLLVG GPAVAAVVVG GLLGYSRAPV EQTDATASSQ
     PERMPANLPT RPDTVRTALE TVPVVKHNDV VNPQDPTVTL MFSGDVTLAE TFKDVMGSNY
     AQTFAEMPEY KQADLAMVNL ENPLTRSTLQ MPGKQFNFKA DPESVEVLKS GGVDIVTLAN
     NHSMDYDAEG LKETLSTLEA AGIEYMGAGT DLTHARRPQI VDVKGQRIAY LAYWGEEYGA
     EANKPGVNNI REERIAEDIR AIRDQVDWVV VNYHWGQELA DFPADWQVKL AHFTIDQGAD
     LIVGHHPHVL QGAEIYKGRA IAYSLGNFIF GGNSRTDYDT AVLRVALKDK QMKVEFLPVE
     VTGYKPKVAQ GARATQILNH ITQISAEFKQ PMPTTTVLDA RTPTTTTPES LAPTPPDPSV
     PAPVPSNSPS FEPSPAPETN QPADSGTGTK GYEKPASPEA VSPSNQLDGA AESLPTPIDP
     NNLDALPGYG GKPMPSPTPL PSIDPMNPDA YLETPSAAPV NPTTNSISPG NTQAQPSPSP
     QLPSFSQPNN SFTNSPSTTP LNFEQANPQN TQGNKSGADS SISISFRIQP NSQSEESEEE
     PLQVALAAPM MW
//