ID K8WEF0_9GAMM Unreviewed; 790 AA.
AC K8WEF0;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Lysine decarboxylase {ECO:0000313|EMBL:EKT55842.1};
GN ORFNames=OO7_12754 {ECO:0000313|EMBL:EKT55842.1};
OS Providencia sneebia DSM 19967.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1141660 {ECO:0000313|EMBL:EKT55842.1, ECO:0000313|Proteomes:UP000010290};
RN [1] {ECO:0000313|EMBL:EKT55842.1, ECO:0000313|Proteomes:UP000010290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19967 {ECO:0000313|EMBL:EKT55842.1,
RC ECO:0000313|Proteomes:UP000010290};
RX PubMed=23145767; DOI=10.1186/1471-2164-13-612;
RA Galac M.R., Lazzaro B.P.;
RT "Comparative genomics of bacteria in the genus Providencia isolated from
RT wild Drosophila melanogaster.";
RL BMC Genomics 13:612-612(2012).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKT55842.1}.
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DR EMBL; AKKN01000010; EKT55842.1; -; Genomic_DNA.
DR RefSeq; WP_008916311.1; NZ_CM001773.1.
DR AlphaFoldDB; K8WEF0; -.
DR PATRIC; fig|1141660.3.peg.2543; -.
DR HOGENOM; CLU_014292_3_0_6; -.
DR OrthoDB; 9761189at2; -.
DR Proteomes; UP000010290; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd00615; Orn_deC_like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR005308; OKR_de-COase_N.
DR InterPro; IPR011193; Orn/lys/arg_de-COase.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR Pfam; PF03709; OKR_DC_1_N; 1.
DR PIRSF; PIRSF009393; Orn_decarb; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR009393-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010290}.
FT DOMAIN 23..137
FT /note="Orn/Lys/Arg decarboxylase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03709"
FT DOMAIN 143..597
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 623..752
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
FT MOD_RES 388
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR009393-1"
SQ SEQUENCE 790 AA; 89095 MW; 1F0AEB023703DF20 CRC64;
MIFNHNVLLI SSQNLDKQHP AKESLEEIGN AVIERGFKVH IVNSIYDGNL LVHEYPKYSA
VGIYWDANNP KMNEQCILFI NTFRKRNAKT PILLLSEKDI TDNVSLDILK EVSEYIYLYS
ETPTFTANRI YTLIHRYAEN LLPPYFKTLK NFTEDGDYYW DCPGHMGGMA YLKHPVGVDF
FHFFGENMMR ADIGVSTAEM GDYLIHAGPS KQSEDIAAEL FGADWTFYGV SGSSGSNRIV
AQGACAADEI AIVDRNCHKS LNHGLTLSQA RPVYLKPTRN GYGLIGPIPT KRLKKHHIDT
LISQSSLSQK AMSSQASYAV ITNCTYDGFC YNVHDVISHL SESAPRLHFD EAWYAYACFH
PLYKNRFAMD AKDTPNRPTI FAVQSTHKML PSLSMASMIH VKKSERAPLN FDDFNDAFMM
HGTTSPYYPI IASIDVAVSM MQGQSGLSLV QESLDEAIAF RKAVVSVKRQ LKEQQQTLPW
FFDVLQPTTV QNSINGDVYC FEDAPSELLS TDPSCWALRA GDDWHGFSDE DLADTDSMLD
PVKVTITCPG ISARGQYQKQ GIPGYIMTKF LDDRRIEIAR TGDYTLLILF SVGITKGKWG
TLLESLLAFK KLYDSEALAV DAIPSLAAHS PLYDKITLKQ LCQEMHEKMY SLDLMKHIND
AVNADPQPVM TPAEAYQKVV RYKTEHIRLD DFSGRIAASM LVPYPPGIPV LMPGERLPAD
NKGIIGYLRA LQDFDKHYPG FEHEIQGINV DENGDFWVRA IIEEEREPEK LPQHVKFKRK
VSTTIKKGRQ
//
