ID K9AEB8_9MICO Unreviewed; 730 AA.
AC K9AEB8;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Choline/carnitine/betaine transporter {ECO:0000313|EMBL:EKU45628.1};
GN ORFNames=C272_13823 {ECO:0000313|EMBL:EKU45628.1};
OS Brevibacterium casei S18.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=1229781 {ECO:0000313|EMBL:EKU45628.1, ECO:0000313|Proteomes:UP000009879};
RN [1] {ECO:0000313|EMBL:EKU45628.1, ECO:0000313|Proteomes:UP000009879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S18 {ECO:0000313|EMBL:EKU45628.1,
RC ECO:0000313|Proteomes:UP000009879};
RA Sharma R., Singh A., Jangir P.K.;
RT "Genome Sequence of Brevibacterium casei S18.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU45628.1}.
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DR EMBL; AMSP01000014; EKU45628.1; -; Genomic_DNA.
DR RefSeq; WP_009380257.1; NZ_AMSP01000014.1.
DR AlphaFoldDB; K9AEB8; -.
DR PATRIC; fig|1229781.4.peg.2771; -.
DR eggNOG; COG1292; Bacteria.
DR Proteomes; UP000009879; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR000060; BCCT_transptr.
DR NCBIfam; TIGR00842; bcct; 1.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009879};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 113..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 79086 MW; 2458EF8EA4DD62DE CRC64;
MSDDSVSDTQ RSAHHHTPPE HTTARRVTRD RFKADARRVG RDAKRVGRDA KRVGRDTGKR
LGALDYARPK RDTATAADPT LDPNAQYPHD IHPILVPGIA IDEQRRRYSI DKVIFAVAGS
LTVAFVIWGI SDPGSVASVA QGAFDWSTLN VGWFFNLVAI VVLVSLLILA FSPYGRIPLG
KDGEKAEFST FAWVAMLFAA GIGIGVLFFG PSEPLTYFIT PPPLTNDPET TEALHGAMAQ
TYYHWGFHAW AMYALVGGAI AYAGYRRGRS LLLSSIFRTL FGKRQTEGFA GKLVDIFAIV
ATLFGTAAAL GIAAMQIGTG VSIVTGVGPM TNAMLVGIIC VLTIGFIISA VSGVSRGIRY
LSSINIVLTI GIVGLVLFLG PTPFLLNLLP SALMEYLGSF FDLMGRSLSW GAETQEFQSV
WTVYYWAWWI SWSPFVGTFI ARISRGRSIR QFILGTIFIP STLLFVAYGI MGGTSIWLYR
EGAAGFTDTM AAPEVFFTLI DNLPFLGWLP AVAIVVLAIF FITSADSASV VMGMLTSRGD
QSPRKWVVVF WGLVMSGIAV VMLLLGDASA LEGLQQLVIV TAVPFALVML FIIVAWVKEL
RTDPMALRRR YAQNAVDNAV VAGAETYGDN FALQVVPTEP GDGANGDIVS EDEAYTDWYQ
RTDEDGEPVG YDYGTGEWED GWTPETKDTA PAEATPDSAS DAESAPDESA DAEPRSASEV
DGEAKSRVTE
//
