ID K9F3D2_9ACTO Unreviewed; 409 AA.
AC K9F3D2;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=HRDC domain-containing protein {ECO:0000259|PROSITE:PS50967};
GN ORFNames=HMPREF9233_00038 {ECO:0000313|EMBL:EKU95950.1};
OS Actinobaculum massiliense ACS-171-V-Col2.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinobaculum.
OX NCBI_TaxID=883066 {ECO:0000313|EMBL:EKU95950.1, ECO:0000313|Proteomes:UP000009888};
RN [1] {ECO:0000313|EMBL:EKU95950.1, ECO:0000313|Proteomes:UP000009888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-171-V-Col2 {ECO:0000313|Proteomes:UP000009888};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Actinobaculum massiliae ACS-171-V-COL2.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU95950.1}.
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DR EMBL; AGWL01000001; EKU95950.1; -; Genomic_DNA.
DR RefSeq; WP_007000256.1; NZ_JH992955.1.
DR AlphaFoldDB; K9F3D2; -.
DR STRING; 202789.GCA_001457435_00107; -.
DR PATRIC; fig|883066.3.peg.40; -.
DR eggNOG; COG0349; Bacteria.
DR HOGENOM; CLU_042387_3_0_11; -.
DR Proteomes; UP000009888; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041605; Exo_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF18305; DNA_pol_A_exoN; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009888}.
FT DOMAIN 227..307
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 45586 MW; 9467ECCA7D418174 CRC64;
MNTSTSASTT SPRPLNRPSG GIPELTNQDI DAAVARLAAG TGAFAIDTER AMGIRYSARA
YLIQIRREGA GTFLVDPVNI EDRLGGLTEL LATDQWILHA ADQDLPSLYE LGLRCTNLFD
TEIAGMILGF EHLSLQWELE ELLGVHLAKE HANSDWSARP LAPELRSYAA LDVELLIPLR
DRLLELLDDA GRTAWCEQEC EHIRTAPPKK PKPDPWRKPA KAAGIRDRRT LAILRELWFA
RDEVARTMDI ATGKVIPDKA LGALAARRPR SLADVENTPT LKRAGRKRYA RPLWKGVARA
WNLDEAELPA ARLPRSSSYP SSTQNWNKHN EVAAERWEII RPAVLERAAE LGIRQDVLLK
PALQKALAWY GWKKRGLEDE LADLGARPWQ IEQVAPAIEA AMRQARSLG
//
