ID   K9F7S9_PEND1            Unreviewed;       918 AA.
AC   K9F7S9;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN   ORFNames=PDIP_88620 {ECO:0000313|EMBL:EKV04122.1};
OS   Penicillium digitatum (strain Pd1 / CECT 20795) (Green mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1170230 {ECO:0000313|EMBL:EKV04122.1, ECO:0000313|Proteomes:UP000009886};
RN   [1] {ECO:0000313|Proteomes:UP000009886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pd1 / CECT 20795 {ECO:0000313|Proteomes:UP000009886};
RX   PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA   Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA   Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT   "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT   postharvest pathogen of citrus.";
RL   BMC Genomics 13:646-646(2012).
CC   -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKV04122.1}.
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DR   EMBL; AKCU01000556; EKV04122.1; -; Genomic_DNA.
DR   RefSeq; XP_014530358.1; XM_014674872.1.
DR   AlphaFoldDB; K9F7S9; -.
DR   GeneID; 26237176; -.
DR   KEGG; pdp:PDIP_88620; -.
DR   HOGENOM; CLU_007149_0_0_1; -.
DR   OrthoDB; 2786196at2759; -.
DR   Proteomes; UP000009886; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR044554; APC2-like.
DR   InterPro; IPR014786; APC2_C.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   Pfam; PF08672; ANAPC2; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SMART; SM01013; APC2; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          532..780
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   918 AA;  102592 MW;  71D07285C54E87FB CRC64;
     MLSTVPLNVG RRRVCVSVFS PASLEAHTQK STSGSQREHT PVESFLESAD SASTFKADSQ
     STSFATIGGS TDAASPEDDT FNQAQQTAKE FLSVPNLGFE LLYNSRDTDG SQVLKEWNRL
     SPPSRETAEA LEYLMRISPW SLFEWYGNDI RRHFLVNIRT GLFKLLKSPE EDGLLRTIVN
     CLQLARRIYL APVVHYLLPL IATPHQGGFL AQLQRTFNTV VQYSLPWKKI SPLLARELTK
     DAVIILGIDT LDEDSDVDRM SLDGTEMERA YSVSYKEWRQ ELPEVQAHMM VEGEDGSVTI
     ARDRLLAFLN ALQLVGLGGD QAQKVFANVM NIMMGDFIRA AYAGEWDSPS TAPQHLEQWV
     ENVYARLAVQ VLAIIHSDPA GAQSGAIEVG FRDVEKWRAM GIARLGKLRV SELFDVVVDW
     PASGGAVEDL RRFTNCSSGA RLYVTSFFSA NLLQRLLHPG ASTVEILQVY ISIIRAFHIL
     DPKGVLLDRI ARPIRRYLRD RDDTVKVIVS GLLADPAAAD GPTATGDTLS ELAAELTKVH
     QHSMQNNMSE LDYDDLYWMP DPVDAAPDYR KSKSVDVIDS LVSLFDSKET FVKEMQTLLA
     GRLIQKRQNY DQEITVLELL KVRFGDSALQ ACEVMLKDIA DSRRLDLTMR NDQIFSGNRK
     QAGVGKLHAK ILSRFFWPEF QEQEFKVPDE ITKLQERYAA CFERRKDSRK LMWRNALGQV
     TVELELENHT FKDEVTTWQA TVIYAFQSDS NEPATRTIPE LADELEMTLP LVRSACLFWV
     SKRILTEVHR DTFRVLEILP TEDEEHYAHA AGDVSDASDS EAGDTANAAA AAEAAAAAAA
     KESAEAAAME KMNVHWQFIV GMLTNQGPMA LTRIVMMLTI AVPGGFPFSN EELREFLGGM
     VSKGKLEIVN GGNYKIVR
//